In a nutshell This study investigated the association between blood transfusions (BT) and inflammation after surgery on the outcomes of patients with colorectal cancer. Researchers suggested that blood transfusion was associated with poorer outcomes for these patients. Some background Colorectal cancer is the third most common cancer worldwide. The...
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A comparison between conventional, laparoscopic and robotic rectal cancer surgery
In a nutshell This study compared the effectiveness of open and non-invasive surgery (NIS) in the treatment of rectal cancer. Researchers suggested that open surgery is associated with improved complete tumor removal, while NIS is associated with fewer complications. Some background Colorectal cancer is one of the most common cancers in the US. The...
Read MoreLooking for patients with colorectal cancer to test a new therapy with tumor infiltrating lymphocytes
In a nutshell This phase 2 trial is examining the effectiveness of tumor-infiltrating lymphocytes (TIL) in the treatment of colorectal cancer. The main outcome to be measured is the tumor response to the treatment. This trial will be conducted in Texas, US. The details Cancer is one of the leading causes of death worldwide. Therapy such as...
Read MoreEncorafenib, cetuximab and binimetinib combined treatment improves survival of patients with advanced colorectal cancer
In a nutshell This study investigated whether treatment with encorafenib (Braftovi), binimetinib (Mektovi), and cetuximab (Erbitux) combined would increase survival in advanced colorectal cancer (CRC). Researchers suggested that this combined therapy increases the survival of patients with metastatic (spread to other parts of the...
Read MoreOxaliplatin in the treatment of rectal cancer after surgery
In a nutshell This study investigated the role of oxaliplatin (Eloxatin) in treating patients with rectal cancer after surgery. Researchers suggested that this drug may be a good option in the treatment of rectal cancer. Some background Chemotherapy is one of the standard treatments for rectal cancer. It usually consists of...
Read MorePanitumumab improves the treatment outcomes of patients with advanced colorectal cancer
In a nutshell This study investigated the effectiveness of panitumumab (Vectibix) in the treatment of advanced colorectal cancer (CRC). Researchers suggested that this drug improved tumor response to the therapy. Some background CRC is one of the most common cancer worldwide. Chemotherapy such as FOLFOXIRI (leucovorin, fluorouracil, oxaliplatin,...
Read MoreA later introduction of anti-EGFR drug is as effective as the standard therapy for advanced colorectal cancer
In a nutshell This study compared the effectiveness of chemotherapy combined with bevacizumab (Avastin) or anti-EGFR drugs for treating advanced colorectal cancer (CRC). Researchers suggested that anti-EGFR later introduced in the treatment of these patients did not impact the outcomes of patients. Some background CRC is the third most common...
Read MoreRegular physical activity is associated with improved outcomes for advanced colorectal cancer
In a nutshell This study investigated the effectiveness of physical activity (PA) on the outcomes of patients with advanced colorectal cancer. Researchers suggested that regular PA is associated with better outcomes for these patients. Some background Colorectal cancer is the third most common cancer worldwide. A significant number of patients...
Read MoreSurgery followed by chemotherapy improves the outcomes of patients with rectal cancer
In a nutshell This study investigated the effectiveness of surgery followed by chemotherapy without chemoradiotherapy (CRT) before surgery to treat rectal cancer. Researchers suggested that this treatment improves the outcomes of these patients. Some background Colorectal cancer is the third most common cancer worldwide. The standard...
Read MoreEpidermal growth factor ointment improves the treatment of skin side effects in patients receiving treatment for colorectal cancer
In a nutshell This study investigated the effectiveness of epidermal growth factor (EGF) ointment to treat skin side effects in patients with colorectal cancer receiving epidermal growth factor receptor (EGFR) inhibitor treatment. Researchers suggested that EGF ointment improves the outcomes and quality of life of these patients. Some background...
Read MoreLooking for participants with advanced colorectal cancer to test a combination therapy
In a nutshell This phase 1/2 trial is examining the effectiveness of standard therapy alone or combined with new drugs as first line treatment for advanced colorectal cancer. The main outcome to be measured will be safety and tumor response to the treatment. The details Colorectal cancer is one of the most common cancers worldwide. A significant...
Read MoreTreatment dose optimisation in patients with advanced colorectal cancer treated with regorafenib
In a nutshell This study investigated the effectiveness and safety of increasing doses of regorafenib (Stivarga) doses in patients with advanced colorectal cancer. Researchers suggested that this method with increasing doses should be used to assess the optimal dose for each patient. Some background Colorectal cancer is the third most common cancer...
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