In a nutshell This study evaluated the effectiveness and safety of robotic versus laparoscopic abdominoperineal resections (APRs) for the treatment of patients with low rectal cancer (RC). The data showed that robotic APRs significantly reduced surgical trauma and promoted recovery after surgery compared with laparoscopic APRs in these patients. Some...
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In a nutshell This study investigated the effect of total neoadjuvant therapy (TNT) versus standard neoadjuvant chemoradiotherapy (CRT) and planned adjuvant chemotherapy on the survival of patients with locally advanced rectal cancer (LARC). The data showed that TNT did not increase survival compared with standard CRT and planned adjuvant...
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In a nutshell This study evaluated the best approach for treating lateral lymph node (LLNs) metastasis in patients with locally advanced rectal cancer (LARC). The data showed that a radiation dose boost is an effective way of increasing the response rate and decreasing recurrence rates in these patients. Some background Rectal cancer (RC) is one...
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In a nutshell The aim of this study was to investigate FOLFIRINOX (oxaliplatin, irinotecan, leucovorin, and fluorouracil) before pre-surgery chemoradiotherapy (CRT) for patients with rectal cancer (RC). The study found that FOLFIRINOX given before CRT and surgery improved the outcomes of these patients. Some background RC can be treated with...
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In a nutshell The aim of this study was to investigate the role of chemotherapy (CT) after surgery in patients with rectal cancer. The study suggests that CT after surgery could improve patient outcomes. Some background Rectal cancer can be treated with surgery to remove the tumor. In general, patients are given CT before the...
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In a nutshell The aim of this study was to evaluate the urinary and sexual function of patients following 2 types of rectal cancer surgery. The study found that in men, robotic surgery resulted in better urinary and sexual function. Some background Rectal cancer can be treated by surgical removal of the tumor. Therapy for rectal cancer has improved...
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In a nutshell This study compared the effectiveness of electron beam radiotherapy (EBR) and high-dose brachytherapy (HDB) during surgery in patients with rectal cancer who underwent an incomplete removal of the cancer. Researchers suggested that HDB was associated with a lower risk of recurrence in these patients. Some background Colorectal...
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In a nutshell This study investigated the effectiveness and safety of computed tomography (CT)-guided radioactive 125Iodine (RI) implantation in patients with recurrent locally advanced rectal cancer (LARC). Researchers suggested that CT-guided RI implantation is a good and safe treatment for patients with LARC that came back...
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In a nutshell This study compared oncological adequateness (OA) and surgery outcomes between open and laparoscopic rectal cancer surgery. Researchers suggested that laparoscopic surgery (LS) is associated with good surgical and oncological outcomes. Some background Colorectal cancer is one of the most common cancers worldwide. Of these, 35% are rectal...
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In a nutshell This trial looked at the use of short-course radiotherapy (RT) followed by chemotherapy (CT) and delayed surgery to reduce distant metastases (tumor spread) in patients with locally advanced rectal cancer (LARC). The trial found that this treatment was more effective in controlling distant metastases when compared to standard...
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In a nutshell This study evaluated the safety and effectiveness of two chemotherapy regimens (SOX and mFOLFOX6) before surgery for rectal cancer (RC) without radiotherapy. The study found that both regimens were safe and effective in these patients. Some background RC is commonly treated with surgery to remove the tumor. Patients with...
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In a nutshell This study evaluated reasons for a delay to ileostomy closure in patients who underwent anterior resection for rectal cancer. This study showed that factors such as having chemotherapy or cancer progression may delay ileostomy closure. Some background The go-to surgical treatment for cancer of the middle and lower rectum involves...
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