In a nutshell The study aimed to investigate the effectiveness and safety of atezolizumab (Tecentriq) versus best supportive care after chemotherapy in patients with resected early-stage non-small-cell lung cancer (NSCLC). The study showed atezolizumab is effective and has better outcomes than best supportive in these...
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In a nutshell This trial was carried to look at the use of erlotinib (Tarceva) with radiotherapy (RT) compared to standard treatment for EGFR-positive non-small cell lung cancer (NSCLC) that cannot be removed surgically. The authors found that erlotinib and RT improved survival without cancer worsening in these patients. Some...
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In a nutshell This study examined the effectiveness and safety of adding durvalumab (Imfinzi) to platinum-etoposide to treat patients with small-cell lung carcinoma (SCLC). The authors found that durvalumab was well-tolerated and improved survival outcomes. Some background Small cell lung carcinoma (SCLC) is a type of lung cancer that...
Read MoreIn a nutshell This phase 2 trial will investigate the effect of gemcitabine (Gemzar) and nivolumab (Opdivo) in patients with metastatic small-cell lung cancer (SCLC). The main outcome will be the radiographic response rate (RRR). This trial is recruiting in North Carolina, US. The details Small cell lung cancer...
Read MoreIn a nutshell This phase 2 trial will investigate the effectiveness of genetically-engineered cell treatment (GECT) in advanced cancer. The main outcome will be the response to treatment. This trial is recruiting at the National Cancer Institute, Maryland, US. The details There are limited treatment options for advanced cancer. One...
Read MoreIn a nutshell This study examined whether patients had a higher risk of thromboembolism depending on the chemotherapy drug they received. The study concluded that patients treated with carboplatin had no difference in the risk of thromboembolism compared to patients treating with cisplatin. Some background Chemotherapy is one of the most well-known...
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In a nutshell This trial examined the antiemetic drug NEPA (Akynzeo) at combating chemotherapy induced nausea and vomiting in patients with lung cancer. The authors concluded that NEPA is effective at reducing nausea and is well tolerated in these patients. Some background For many cancers, chemotherapy is the gold standard for treatment....
Read MoreIn a nutshell This study compared the effectiveness and safety of nivolumab (Opdivo) and docetaxel (Taxotere) for the treatment of advanced squamous-cell non-small-cell lung cancer (NSCLC). The study concluded that nivolumab is more effective and safer than docetaxel for this type of cancer. Some background PD-L1 is a protein that...
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In a nutshell This study compared two treatment strategies for advanced non-small cell lung cancer: platinum analog chemotherapy plus the drug bevacizumab (avastin) versus platinum analog chemotherapy alone. Some background Treatment for advanced non-small cell lung cancer typically involves treatment with chemotherapy. Standard chemotherapy...
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