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Type(s) of chemotherapy-ABVD Posts on Medivizor

Does combining brentuximab vedotin with chemotherapy reduce the risk of consolidative radiotherapy for patients with early-stage unfavorable-risk Hodgkin lymphoma?

Does combining brentuximab vedotin with chemotherapy reduce the risk of consolidative radiotherapy for patients with early-stage unfavorable-risk Hodgkin lymphoma?

Posted by on Jun 6, 2021 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated whether brentuximab vedotin (Adcedris; BC) + AVD (doxorubicin, vinblastine, and dacarbazine) chemotherapy combination resulted in a reduction or elimination of consolidative radiotherapy in early-stage unfavorable-risk Hodgkin lymphoma (HL). The data showed that the BV+AVD combination with and without...

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Is PET-guided exclusion of radiotherapy an appropriate treatment regimen for unfavorable early-stage Hodgkin lymphoma?

Is PET-guided exclusion of radiotherapy an appropriate treatment regimen for unfavorable early-stage Hodgkin lymphoma?

Posted by on Mar 21, 2021 in Hodgkin's lymphoma | 0 comments

In a nutshell The authors investigated the impact of removing radiotherapy (RT) from treatment regimens in patients with early-stage unfavorable Hodgkin lymphoma (HL). This study concluded that this treatment regimen is just as effective as the standard of care.  Some background Chemotherapy and consolidation RT is the standard of care for...

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What are the effects of lenalidomide, doxorubicin, vinblastine and dacarbazine in Hodgkin lymphoma?

What are the effects of lenalidomide, doxorubicin, vinblastine and dacarbazine in Hodgkin lymphoma?

Posted by on Jan 12, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the effects of adding lenalidomide (Revlimid) to doxorubicin (Adriamycin), vinblastine (Velban), and dacarbazine (DTIC-Dome) treatment for older patients with Hodgkin lymphoma (HL). The main finding was that this combination is effective but severe side-effects may be experienced. Some background HL is a cancer...

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Searching for patients with early stage Hodgkin lymphoma to try brentuximab vedotin and nivolumab

Posted by on Jan 9, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study is investigating the effectiveness of brentuximab vedotin (Adcetris) and nivolumab (Opdivo) in early-stage Hodgkin lymphoma (HL). The main outcome that will be measured will be survival without cancer worsening after 18 months.  The details There are many different treatments for HL. Each treatment or combination of...

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Do ACE inhibitors help with anthracycline-induced cardiotoxicity in leukemia and lymphoma?

Posted by on Dec 6, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate if enalapril influences anthracycline-induced cardiotoxicity in children with leukemia and lymphoma. This study concluded that enalapril has a role in reducing anthracycline-induced cardiotoxicity in these patients. Some background Anthracyclines are a class of chemotherapy drugs that can be used for...

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Does anti-PD1 therapy change the effectiveness of chemotherapy in unresponsive Hodgkin lymphoma?

Posted by on Jun 28, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the effects of chemotherapy alone or chemotherapy plus anti-PD1 therapy in patients with relapsing/refractory (RR) Hodgkin's Lymphoma. The main finding was that anti-PD1 treatment enhances the effectiveness of chemotherapy in these patients. Some background Stem cell transplant (SCT) and...

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What are the long-term outcomes for HL patients who experience treatment failure after an autologous stem cell transplant?

What are the long-term outcomes for HL patients who experience treatment failure after an autologous stem cell transplant?

Posted by on Apr 18, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study analyzed the survival outcomes of Hodgkin’s lymphoma (HL) patients who experience treatment failure after high-dose chemotherapy (HDC) and autologous hematopoietic stem cell transplantation (autoSCT). This study concluded that a second stem cell transplant with or without brentuximab vedotin (Adcetris) may lead to better...

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Can white blood cell count ratios help predict outcomes for newly diagnosed HL patients receiving PET2-mediated treatment?

Can white blood cell count ratios help predict outcomes for newly diagnosed HL patients receiving PET2-mediated treatment?

Posted by on Apr 6, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the impact of white blood cell counts on the outcomes of newly diagnosed Hodgkin’s lymphoma (HL) patients receiving treatment mediated by PET2 (PET scanning after 2 cycles of chemotherapy). This study concluded that ratios of different types of white blood cells combined with PET2 can be a meaningful...

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Outcomes for Hodgkin lymphoma patients treated with combined modality treatment

Outcomes for Hodgkin lymphoma patients treated with combined modality treatment

Posted by on Feb 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study looked at the long term outcomes for patients with Hodgkin lymphoma who were treated with radiation therapy. The study concluded that patients treated with radiation therapy had better outcomes compared to patients not treated with radiation therapy.  Some background Patients with Hodgkin lymphoma (HL) generally have good...

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