Type(s) of breast cancer-Lobular carcinoma Page 2 Posts on Medivizor
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Type(s) of breast cancer-Lobular carcinoma Posts on Medivizor

Recurrence of breast cancer in the central nervous system (CNS) associated with trastuzumab treatment

Posted by on Jul 20, 2013 in Breast cancer | 0 comments

In a nutshell This large analysis determined the risk of CNS metastases as the first site of recurrence in patients with HER2-positive breast cancer who received trastuzumab (herceptin). Some background Breast cancer recurrence (return of the cancer) may occur near the site of the original cancer, or at other distant locations. The central nervous...

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The effect of adding lapatinib to paclitaxel chemotherapy on survival in HER2 positive metastatic breast cancer patients

Posted by on Jul 6, 2013 in Breast cancer | 0 comments

In a nutshell This phase III clinical trial evaluated the effects on survival of the drug lapatinib in combination with a standard chemotherapy agent called paclitaxel in newly diagnosed HER2 positive metastatic breast cancer patients.  Some background Some breast cancer cells have on their surface a protein (receptor) called human epidermal...

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Evaluating outcomes for a new radiotherapy technique in patients with breast cancer

Posted by on Jun 26, 2013 in Breast cancer | 0 comments

In a nutshell This study looks at survival rates and side effects after 5 years following a newer radiotherapy procedure in patients with breast cancer. This radiotherapy procedure is called accelerated partial breast irradiation (ABPI) delivered using 3-dimentional conformal external beam radiation therapy (3D-CRT). Some background Treatment for...

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Phase 3 clinical trial of evaluating lapatinib in patients with HER2 positive breast cancer

Posted by on Jun 25, 2013 in Breast cancer | 0 comments

In a nutshell This phase 3 clinical trial investigated the safety and efficacy of lapatinib (Tykerb) in women with HER2 positive early-stage breast cancer. Some background HER2-positive (HER2+) breast cancer is a type of cancer where a protein named human epidermal growth factor receptor 2 (HER2) is present on the surface of the breast...

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Evaluating chemotherapy options for patients with triple negative breast cancer

Posted by on Jun 17, 2013 in Breast cancer | 0 comments

In a nutshell This article looked at the use of a platinum based chemotherapy (cisplatin) to a non-platinum based chemotherapy for patients with triple negative breast cancer. Some background Most breast cancers have on their surface some proteins called receptors that help the breast cancers grow. These can be hormone receptors (estrogen or...

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Phase 3 clinical trial comparing the addition of anastrozole versus tamoxifen to goserelin therapy before surgery for patients with early-stage breast cancer

Posted by on Jun 5, 2013 in Breast cancer | 0 comments

In a nutshell This phase 3 clinical trial compared the safety and efficacy of two different combination treatments in women with early stage breast cancer: anastrozole (Arimidex) plus goserelin (Zoladex) versus tamoxifen (Nolvadex) plus goserelin. Some background An estrogen-receptor positive (ER+) breast cancer requires estrogen (the primary...

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Does radiation therapy improve survival in early stage breast cancer patients treated with lumpectomy and tamoxifen?

Posted by on Jun 2, 2013 in Breast cancer | 0 comments

In a nutshell This study evaluated whether there is any benefit from radiation therapy (RT) in women over the age of 70 with early stage breast cancer treated with lumpectomy (surgical removal of the cancerous lump) and tamoxifen. Some background Breast cancer in older patients is often fueled by estrogen, a female sex hormone. These cancer...

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Risk of Heart Failure after Anthracycline (Adriamycin/Daunomycin) and Trastuzumab (Herceptin) Treatments for Breast Cancer

Posted by on Mar 19, 2013 in Breast cancer | 0 comments

In a nutshell This study evaluated the risk of heart disease associated with two commonly prescribed treatments for breast cancer. The main finding was that Trastuzumab (Herceptin) and Anthracycline (Adriamycin/Daunomycin) treatments are associated with a higher risk of heart failure or ‘cardiomyopathy’. Some background Anthracyclines...

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Efficacy and adherence to a lifestyle modification program in sedentary breast cancer survivors

Posted by on Mar 7, 2013 in Breast cancer | 0 comments

In a nutshell This study evaluated the efficacy of home-based lifestyle counseling and coaching program in achieving adequate lifestyle changes in older sedentary breast cancer survivors.  Some background Older breast cancer survivors are at risk of developing secondary cancers, heart diseases and declining self-care capacity. Previous...

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Personalized Tamoxifen Treatments

Posted by on Mar 4, 2013 in Breast cancer | 0 comments

Most patients on Tamoxifen receive a standard dose of medication. However, patients may benefit more from individually adjusted doses. This paper highlights potential strategies for personalized Tamoxifen treatments. Tamoxifen is not active on its own. Once ingested, the body converts it into other substances (metabolites). Some of these...

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