In a nutshell This study evaluated the efficacy and safety of accelerated partial breast irradiation (APBI) using the MammoSite device for the treatment of patients after breast conserving surgery. Some background After breast conserving surgery (BCS; surgical removal of the tumor and surrounding tissue without removal of the entire breast),...
Read MoreIn a nutshell This large analysis determined the risk of CNS metastases as the first site of recurrence in patients with HER2-positive breast cancer who received trastuzumab (herceptin). Some background Breast cancer recurrence (return of the cancer) may occur near the site of the original cancer, or at other distant locations. The central nervous...
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In a nutshell This study analyzed the occurrence of distance metastasis (the spread of the cancer to distant organs) in early stage breast cancer patients after breast conservation therapy (BCT). This study also showed the pattern of spread to these distant organs. Some background Early-stage...
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In a nutshell In this trial researchers examined whether the use of neoadjuvant chemotherapy (before surgery) influenced survival or recurrence rates in women undergoing breast conserving therapy for breast cancer. Some background Neoadjuvant chemotherapy (NCT) refers to chemotherapy treatments received prior to surgery. This approach is often...
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In a nutshell This study investigated the efficacy of using the ductal carcinoma in situ (DCIS) score to predict the risk of recurrence (return of the cancer) in patients with DCIS. Some background Ductal carcinoma in situ (DCIS) is the presence of abnormal cells inside the milk ducts (vessels) of the breast. In DCIS these abnormal cells are...
Read MoreIn a nutshell Tamoxifen is one of the main drugs used for hormonal treatment of breast cancer. The aim of this article was to establish the value of Tamoxifen as a preventive agent for women who have high chances of developing breast cancer. Main finding: Tamoxifen notably reduces the risk of developing breast cancer in easily identifiable higher risk...
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In a nutshell This article reports long-term results of the UK/ANZ DCIS (“UK/Australia and New Zealand Ductal Carcinoma in Situ”) trial. This study investigated the use of radiation treatment and Tamoxifen treatments in DCIS. Some background Ductal carcinoma in situ (DCIS) is the most common type of non-invasive breast cancer....
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