In a nutshell This study looked at the use of two types of stem cell transplant (SCT) in the treatment of T-cell lymphoma. It found that both haploidentical and umbilical cord blood SCT were good options for these patients. Some background T-cell lymphoma is a cancer affecting a certain type of blood cell called T-cells. T-cells are...
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In a nutshell This study assessed the effectiveness and safety of geptanolimab (GB226) in relapsed/refractory (r/r) peripheral T cell lymphoma (PTCL). The authors concluded that geptanolimab showed promising activity and manageable safety in these patients. Some background Peripheral T cell lymphoma (PTCL) is a rare subtype of non-Hodgkin...
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In a nutshell This study investigated the effectiveness and safety of GDP (gemcitabine, dexamethasone, and cisplatin) and ICE (ifosfamide, carboplatin, and etoposide) regimens as salvage therapy in patients with relapsed/refractory aggressive lymphoma. The data showed that both the GDP and ICE regimens are suitable options for relapsed/refractory...
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In a nutshell This study examined the effectiveness of a modified anti-nausea and vomiting treatment for patients with aggressive non-Hodgkin lymphoma (NHL) receiving high-dose (HD) chemotherapy. The results showed that netupitant/palonosetron (NEPA; Akynzeo) alone was very effective and safe for these patients. Some background Chemotherapy...
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In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) have very...
Read MoreIn a nutshell This study evaluated two different dosing approaches for busulfan (Busilvex) chemotherapy for patients with non-Hodgkin lymphoma (NHL) before an autologous stem cell transplant (SCT). The authors found that personalizing treatment dose for these patients was more effective than conventional weight-based dosing. Some background...
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