Type of leukemia-Chronic Myeloid Leukemia (CML) Posts on Medivizor
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Type of leukemia-Chronic Myeloid Leukemia (CML) Posts on Medivizor

Evaluating the long-term effectiveness and safety of bosutinib versus imatinib in patients with newly diagnosed chronic phase chronic myeloid leukemia.

Evaluating the long-term effectiveness and safety of bosutinib versus imatinib in patients with newly diagnosed chronic phase chronic myeloid leukemia.

Posted by on Dec 30, 2022 in Leukemia | 0 comments

In a nutshell This study evaluated the long-term effectiveness and safety of bosutinib (Bosulif) versus imatinib (Gleevec) in patients with newly diagnosed chronic phase (CP) chronic myeloid leukemia (CML). The data showed that bosutinib had better effectiveness than imatinib in these patients. Some background CML is a type of cancer that starts...

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Evaluating ponatinib treatment in any phase of treatment in patients with chronic myeloid leukemia resistant or intolerant to other tyrosine kinase inhibitors

Evaluating ponatinib treatment in any phase of treatment in patients with chronic myeloid leukemia resistant or intolerant to other tyrosine kinase inhibitors

Posted by on Sep 18, 2022 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of ponatinib (Iclusig) in patients with chronic myeloid leukemia (CML) who were resistant or intolerant to previous tyrosine kinase inhibitors (TKIs).  This study concluded that ponatinib was effective in heavily pretreated patients when administered in any phase of...

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Identifying the factors that influence severity of fatigue in patients with chronic myeloid leukemia treated with targeted therapy.

Identifying the factors that influence severity of fatigue in patients with chronic myeloid leukemia treated with targeted therapy.

Posted by on Aug 7, 2021 in Leukemia | 0 comments

In a nutshell This study explored the factors that affect fatigue severity and the relationship between fatigue severity and health-related quality of life (HRQoL) among patients with chronic myeloid leukemia (CML). The data showed that worse fatigue was associated with high body mass index (BMI; weight in relation to height) and more sleep...

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Evaluating antithymocyte globulin in preventing graft-versus-host-disease after matched sibling donor transplantation

Evaluating antithymocyte globulin in preventing graft-versus-host-disease after matched sibling donor transplantation

Posted by on Aug 16, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the role of antithymocyte globulin in preventing graft-versus-host disease after matched sibling donor transplantation.  This study concluded that this treatment can reduce the occurrence of graft-versus-host-disease in these patients.   Some background One...

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Impact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide

Impact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide

Posted by on Jun 21, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan). This study concluded that cryopreservation (CP) does not affect the outcomes of HSCT in these patients....

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Managing patients with chronic myeloid leukemia who fail responding to second generation tyrosine kinase inhibitors

Managing patients with chronic myeloid leukemia who fail responding to second generation tyrosine kinase inhibitors

Posted by on Jun 7, 2020 in Leukemia | 0 comments

In a nutshell The report recommends how to manage patients with chronic-phase chronic myeloid leukemia (CP-CML) who failed to respond to 2nd generation tyrosine kinase inhibitors (TKIs). The authors suggested to consider patient-specific factors and personalize treatment for such patients. Some background TKIs deactivate cancerous enzymes which cause...

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Switching from frontline second-generation tyrosine kinase inhibitor treatment in chronic myeloid leukemia

Switching from frontline second-generation tyrosine kinase inhibitor treatment in chronic myeloid leukemia

Posted by on May 24, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate second treatments in patients with chronic myeloid leukemia (CML) who had been initially treated with second-generation tyrosine kinase inhibitors (TKI).  This study concluded that switching from second-generation TKIs in these patients was relatively uncommon.   Some background...

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Kidney function in patients with chronic myeloid leukemia after stopping tyrosine kinase inhibitors

Kidney function in patients with chronic myeloid leukemia after stopping tyrosine kinase inhibitors

Posted by on May 17, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate kidney function in patients with chronic-phase (CP) chronic myeloid leukemia (CML) before and after tyrosine kinase inhibitor (TKI) treatment.  This study concluded that long-term TKI treatment leads to kidney side effects in these patients that may be irreversible after stopping...

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