In a nutshell This study aimed to investigate the rate of deep molecular response in patients with newly diagnosed chronic myeloid leukemia who were treated with nilotinib. This study concluded that good molecular response rates are seen in these patients. Some background Molecular response (MR) is a measure of the levels of BCR-ABL1 gene in leukemia...
Read MoreType of leukemia-Chronic Myeloid Leukemia (CML) Posts on Medivizor
Allogenic hematopoietic stem cell transplantation as treatment for patients with BCR-ABL1-negative atypical chronic myeloid leukemia
In a nutshell This study aimed to investigate if allogeneic hematopoietic stem cell transplant is an effective treatment for atypical chronic myeloid leukemia. This study concluded that this treatment is effective in these patients. Some background Atypical chronic myeloid leukemia (aCML) and chronic neutrophilic leukemia (CNL) are cancers...
Read MoreDoes cancer and stem cell transplants change taste in children?
In a nutshell This study looked at the changes in the sense of taste of children with cancer and those who received a stem cell transplant. Researchers found that taste changes in these patients were common. Some background Cancer is often treated with powerful drugs or stem cell transplant. These may have strong side effects. In children, it is...
Read MoreDoes cancer and stem cell transplants change taste in children?
In a nutshell This study looked at the changes in the sense of taste of children with cancer and those who received a stem cell transplant. Researchers found that taste changes in these patients were common. Some background Cancer is often treated with powerful drugs or stem cell transplant. These may have strong side effects. In...
Read MoreUsing steroid medication to prevent stem cell transplant complications in patients with leukemia
In a nutshell This study looked at the effects of using steroid medication to prevent complications after stem cell transplant and improve survival in patients with leukemia. Researchers found that low-dose steroids improved outcomes in these patients. Some background Leukemia is a cancer of the blood-forming tissues such as the bone...
Read MoreCan imatinib levels predict the outcomes for patients with chronic myeloid leukemia?
In a nutshell This study aimed to investigate if imatinib (Gleevec) levels can predict responses for patients with newly diagnosed chronic myeloid leukemia. This study concluded that imatinib trough levels influenced treatment responses in these patients. Some background Imatinib is a targeted treatment used to treat chronic...
Read MoreDo high and low intensity treatments have similar effectiveness in CML?
In a nutshell This study compared the effectiveness of regular myeloablative conditioning (MAC; chemotherapy that kills cells in the bone marrow, including cancer cells before a transplant) with reduced-intensity conditioning (RIC) in the treatment of chronic myeloid leukemia. Researchers found that RIC had similar effectiveness and less risk of...
Read MoreSurvival from transplant of donor bone marrow versus donor blood sample in leukemia treatment
In a nutshell This study compared the safety and effectiveness of donor peripheral blood (PB) with bone marrow (BM) transplant in the treatment of leukemia. Researchers found that bone marrow transplants are safer and more effective in the treatment of leukemia. Some background Leukemia is a cancer of the bone marrow. It may lead to abnormal immune...
Read MoreUsage and safety of drug treatment in chronic myeloid leukemia
In a nutshell This study aimed to assess the usage and safety of biological treatment to treat chronic myeloid leukemia (CML). Researchers found that nilotinib (Tasigna) has a better profile as a first-line drug in the treatment of CML. Some background Chronic myeloid leukemia is a cancer of the bone marrow. This leads to abnormal immune...
Read MoreDo ACE inhibitors help with anthracycline-induced cardiotoxicity in leukemia and lymphoma?
In a nutshell This study aimed to investigate if enalapril influences anthracycline-induced cardiotoxicity in children with leukemia and lymphoma. This study concluded that enalapril has a role in reducing anthracycline-induced cardiotoxicity in these patients. Some background Anthracyclines are a class of chemotherapy drugs that can be used for...
Read MoreThe safety and effectiveness of bosutinib in patients with chronic myeloid leukemia
In a nutshell This study looked at the safety and effectiveness of bosutinib (Bosulif) in the treatment of chronic myeloid leukemia (CML). Researchers found that bosutinib was effective in patients who have failed other similar drug treatments. Some background Chronic myeloid leukemia (CML) is a cancer of the bone marrow. This can lead to abnormal...
Read MoreWhole body vibration during chemotherapy for leukemia and lymphoma
In a nutshell This study examined the effectiveness of vibration therapy on patients receiving chemotherapy for leukemia and lymphoma. Researchers found that vibration therapy improved daily function in these patients. Some background Exercise is proven to be effective in improving outcomes of patients with cancer. Chemotherapy treatment can make...
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