In a nutshell This trial is examining the effectiveness of ibrutinib (Imbruvica) and obinutuzumab (Gazyva) with or without venetoclax (Venclexta) in the treatment of chronic lymphocytic leukemia (CLL). The main outcome to be measured will be survival without cancer growing or spreading. This trial is recruiting in various places around the...
Read MoreType of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor
Stem cell transplant for blood cancers: mother vs unrelated donors
In a nutshell This study compared the effectiveness of stem cell transplant from a mother donor compared to an unrelated donor in the treatment of cancers of the blood. Researchers found that mother donors could have some better outcomes but with an increased risk of a reaction to the transplant. Some background Cancers of the blood often involve the...
Read MoreGuidelines for the diagnosis and management of chronic lymphocytic leukemia/small lymphocytic lymphoma
In a nutshell This study was a review of the most recent guidelines of diagnosis and treatment of chronic lymphocytic leukemia (CLL) that has transformed into aggressive lymphoma. Some background Chronic lymphocytic leukemia is a cancer of the bone marrow and immune system. Over time, it may develop into a cancer of the immune tissues called a...
Read MoreThe use of reduced ibrutinib doses in patients with chronic lymphocytic leukemia
In a nutshell This study aimed to investigate the effects of reducing the dose of ibrutinib on the outcomes of patients with chronic lymphocytic leukemia. This study concluded that dose reduction has no significant effect on the outcomes of these patients. Some background Ibrutinib (Imbruvica) is a targeted therapy used to treat chronic...
Read MoreDoes cancer and stem cell transplants change taste in children?
In a nutshell This study looked at the changes in the sense of taste of children with cancer and those who received a stem cell transplant. Researchers found that taste changes in these patients were common. Some background Cancer is often treated with powerful drugs or stem cell transplant. These may have strong side effects. In...
Read MoreRituximab to treat unresponsive chronic lymphocytic leukemia in a real-world setting
In a nutshell This study examined the safety and effectiveness of rituximab (Rituxan) to treat relapsed or unresponsive chronic lymphocytic leukemia (CLL) in a real-world setting. Authors concluded that rituximab was safe and effective in these patients. Some background Chronic lymphocytic leukemia is a cancer of the immune system. It...
Read MoreComparing ibrutinib and ofatumumab in patients with previously treated chronic lymphocytic leukemia
In a nutshell This study aimed to investigate patient well-being and patient-reported outcomes in previously treated patients with chronic lymphocytic leukemia who receive ibrutinib (Imbruvica) or ofatumumab (Arzerra). They concluded that ibrutinib can improve quality of life while prolonging survival in these patients. Some background...
Read MoreCan pretreatment with obinutuzumab reduce side effects of CLL treatment?
In a nutshell This study looked at the use of obinutuzumab (Gazyva) pretreatment to reduce side effects of chemotherapy in patients with chronic lymphocytic leukemia (CLL). Researchers found that obinutuzumab pretreatment is effective in reducing chemotherapy side effects in these patients. Some background Treatment of CLL involves...
Read MoreEvaluating ibrutinib and obinutuzumab combination for the treatment of chronic lymphocytic leukemia
In a nutshell This study aimed to investigate the effectiveness of ibrutinib and obinutuzumab combination in patients with chronic lymphocytic leukemia. This study concluded that this combination is safe and highly effective as a treatment for these patients. Some background Obinutuzumab (Gazyva) and ibrutinib (Imbruvica)...
Read MoreDoes older age affect outcome in CLL?
In a nutshell This study wanted to assess the outcomes of chemoimmunotherapy in older patients with chronic lymphocytic leukemia (CLL). Researchers found that chemoimmunotherapy is safe and effective in these patients. Some background Chronic lymphocytic leukemia is a cancer of the bone marrow. It is often associated with older patients and...
Read MoreWhole body vibration during chemotherapy for leukemia and lymphoma
In a nutshell This study examined the effectiveness of vibration therapy on patients receiving chemotherapy for leukemia and lymphoma. Researchers found that vibration therapy improved daily function in these patients. Some background Exercise is proven to be effective in improving outcomes of patients with cancer. Chemotherapy treatment can make...
Read MoreComparing chemoimmunotherapy and ibrutinib treatment in patients with chronic lymphocytic leukemia
In a nutshell This study aimed to compare the outcomes of patients with chronic lymphocytic leukemia who received chemoimmunotherapy or ibrutinib. This study suggested that ibrutinib may have more favorable outcomes for these patients when compared to chemoimmunotherapy. Some background Chemoimmunotherapy (CIT) is a treatment option that can be used...
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