Type of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor
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Type of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor

A new treatment combination for patients with relapsed/refractory chronic lymphocytic leukemia

Posted by on Apr 18, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness of venetoclax (Venclexta) and rituximab (Rituxan) treatment in patients with relapsed/refractory chronic lymphocytic leukemia. This study concluded that venetoclax-rituximab treatment was effective for these patients.     Some background Chronic lymphocytic leukemia...

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First-line treatment with ibrutinib – a review

Posted by on Mar 11, 2018 in Leukemia | 0 comments

In a nutshell This study outlined recent evidence on the use of ibrutinib (Imbruvica) for chronic lymphocytic leukemia (CLL). Some background Tyrosine kinase inhibitor therapy is a type of immunotherapy that blocks signals needed for tumors to grow. This includes the Bruton tyrosine kinase inhibitor ibrutinib. Ibrutinib blocks a signal that keeps the...

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Rituximab, cladribine and cyclophosphamide: Early results of a new treatment combination with and without maintenance therapy

Posted by on Mar 11, 2018 in Leukemia | 0 comments

In a nutshell This study examined a new treatment combination known as RCC followed by rituximab (Rituxan) maintenance therapy for chronic lymphocytic leukemia (CLL). These results support the safety and effectiveness of RCC followed by rituximab maintenance therapy. Risk factors of disease progression were identified. Some background The chemotherapy...

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Promising early results with venetoclax in patients previously treated with idelalisib

Posted by on Jan 18, 2018 in Leukemia | 0 comments

In a nutshell This study examined venetoclax (Venclexta) for patients with chronic lymphocytic leukemia (CLL) previously treated with idelalisib (Zydelig). Researchers reported good response rates and a low rate of side effects for venetoclax after idelalisib. Some background Targeted therapy is the standard treatment of CLL. This includes the...

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Good response rates to venetoclax in patients previously treated with ibrutinib

Posted by on Jan 12, 2018 in Leukemia | 0 comments

In a nutshell This study examined venetoclax (Venclexta) for patients with chronic lymphocytic leukemia (CLL) previously treated with ibrutinib (Imbruvica). Researchers reported good disease control and a low rate of side effects venetoclax after ibrutinib. Some background Targeted therapy is the standard treatment of CLL. This includes the Bruton...

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CAR T-Cells and HIV: What’s the Connection?

CAR T-Cells and HIV: What’s the Connection?

Posted by on Jan 5, 2018 in Blog, Breast cancer, Colorectal cancer, Hodgkin's lymphoma, Leukemia, Lung cancer, Lymphoma, Melanoma, Multiple Myeloma, Non-Hodgkin lymphoma, Prostate cancer | 1 comment

It has taken decades of work for researchers to find ways to activate the immune system to treat cancer (what we now call immuno-oncology or I-O). Much of that work has been poorly funded. Largely, it has been the result of researchers getting experience in other disciplines (like infectious disease) and then transferring that expertise to oncology...

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What Are the Common Symptoms of CLL?

Posted by on Jan 3, 2018 in Leukemia | 0 comments

Video information: While some chronic lymphocytic leukemia (CLL) patients are asymptomatic, the disease can cause a wide range of symptoms—and indicate disease progression. Dr. Stephen Spurgeon, from the OHSU Knight Cancer Institute, describes common CLL symptoms and their implications. Transcript Please remember the opinions expressed on...

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CLL With a 17p Deletion: What Is the Treatment Plan?

Posted by on Jan 3, 2018 in Leukemia | 0 comments

Video information: Precision medicine allows for treatment plans to line up with a specific genetic profile. Find out from Dr. Michael Keating what is used to target CLL patients with a 17p deletion and when treatment should generally start. Dr. Keating also shares other genetic mutations to be aware of, and which tests are used to locate...

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Detecting, Identifying and Treating Subtypes of CLL

Posted by on Jan 3, 2018 in Leukemia | 0 comments

Video information: Every patient’s CLL is different, so how do doctors tell which CLL treatment is best? Dr. Kathryn Kolibaba, with Compass Oncology, and Dr. Stephen Spurgeon, from OHSU Knight Cancer Institute, discuss modern tests used to distinguish subtypes of CLL and find a therapy to match. The experts also share their thoughts on the...

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Decoding Monoclonal Antibodies

Posted by on Jan 3, 2018 in Leukemia | 0 comments

Video information: What are monoclonal antibodies targeting in the fight against CLL? Join us to hear from experts, Dr. Stephen Spurgeon and Dr. Jeff Sharman, as they dissect the scientific terminology that describes the monoclonal antibody family and their intended targets in the body. Transcript: Andrew Schorr: We have all these other drugs...

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An analysis comparing reduced-intensity conditioning and myeloablative therapy for CLL

Posted by on Dec 30, 2017 in Leukemia | 0 comments

In a nutshell This study analyzed the results of 37 studies comparing myeloablative therapy and reduced intensity conditioning (RIC) before stem cell transplantation in patients with chronic lymphocytic leukemia (CLL). This study concluded that RIC was associated with lower mortality and better survival compared to myeloablative therapy. Some...

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