Type of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor
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Type of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor

Combining obinutuzumab and chlorambucil in unfit patients with chronic lymphocytic leukemia

Posted by on Mar 24, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the effectiveness of combining obinutuzumab (Gazyva) and chlorambucil (Leukeran) (O-Clb) to treat physically unfit patients with chronic lymphocytic leukemia (CLL). The authors found that O-Clb is a safe and effective initial treatment for unfit patients with low-risk CLL in a real-world setting. Some background...

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Evaluating the risk of infection associated with ibrutinib treatment in patients with chronic lymphocytic leukemia

Posted by on Mar 20, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the risk of infection with ibrutinib treatment in B-cell malignancies such as chronic lymphocytic leukemia.  This study concluded that ibrutinib was associated with a higher risk of infections in these patients. Some background B-cell malignancies such as chronic...

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Venetoclax in elderly patients with relapsed or unresponsive chronic lymphocytic leukemia

Posted by on Feb 25, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate if venetoclax was safe and effective in older patients with relapsed/refractory chronic lymphocytic leukemia outside of clinical trials. This study concluded that venetoclax is safe and effective in these patients. Some background Chronic lymphocytic leukemia (CLL) is commonly diagnosed in older people....

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Evaluating the effects of venetoclax and obinutuzumab in patients with untreated chronic lymphocytic leukemia

Posted by on Feb 11, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the treatment benefits of venetoclax (Venclexta) and obinutuzumab (Gazyva) in patients with untreated chronic lymphocytic leukemia (CLL) and coexisting medical conditions. The main finding was that the combination therapy improved outcomes in these patients. Some background Most patients with CLL are older...

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Comparing time to next treatment, health care resource utilization and costs between patients with chronic lymphocytic treated with ibrutinib or chemoimmunotherapy

Posted by on Jan 27, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to compare health care costs, resource utilization and time to the next treatment in patients with chronic lymphocytic leukemia who received ibrutinib or chemoimmunotherapy.  This study concluded that ibrutinib in these patients was associated with lower medical costs and longer time...

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Evaluating blood or marrow transplantation with post-transplant cyclophosphamide in chronic lymphocytic leukemia

Posted by on Dec 15, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effect of post-transplant cyclophosphamide on allogeneic blood or marrow transplant in patients with chronic lymphocytic leukemia.   This study concluded that this treatment approach is safe and effective for these patients.   Some background Allogeneic blood or...

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Surviving cancer – is there a greater risk of cardiovascular disease long-term?

Posted by on Sep 16, 2019 in Leukemia | 0 comments

In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors.  They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...

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Looking for patients with chronic lymphocytic leukemia to test acalabrutinib-obinutuzumab combination

Posted by on Apr 22, 2019 in Leukemia | 0 comments

In a nutshell This phase 2 trial is evaluating the effectiveness of acalabrutinib (Calquence) with or without obinutuzumab (Gazyva) for chronic lymphocytic leukemia (CLL). The main outcome to be measured will be the number of patients who have a complete disappearance of all signs of cancer. This study is being conducted in Phoenix, Arizona,...

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