Type of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor
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Type of leukemia-Chronic lymphocytic leukemia (CLL) Posts on Medivizor

The effect of other conditions on ibrutinib treatment of CLL

Posted by on Jun 26, 2018 in Leukemia | 0 comments

In a nutshell The study looked at the impact of other medical conditions (comorbidities) on the effectiveness of ibrutinib (Imbruvica) in the treatment of chronic lymphocytic leukemia (CLL). The study concluded that having a number of other conditions was associated with a poorer prognosis in CLL patients treated with ibrutinib. Some background...

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Combining obinutuzumab and bendamustine for chronic lymphocytic leukemia patients

Posted by on Jun 23, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness of an obinutuzumab and bendamustine combination in chronic lymphocytic leukemia patients. This study concluded that this combination appears to be effective in these patients and has manageable side effects. Some background Obinutuzumab (Gazyva) is a monoclonal antibody. Monoclonal...

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Lenalidomide and blood clots: low risk in CLL and NHL

Posted by on May 22, 2018 in Leukemia | 0 comments

In a nutshell This study examined the risk of venous thromboembolism (VTE, a blood clot that forms in the veins of the legs, arms, or groin) in patients treated with lenalidomide (Revlimid). The study concluded that the risk of VTE was low with lenalidomide treatment. Some background Lenalidomide is an effective treatment already used in multiple...

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A new treatment combination for patients with relapsed/refractory chronic lymphocytic leukemia

Posted by on Apr 18, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness of venetoclax (Venclexta) and rituximab (Rituxan) treatment in patients with relapsed/refractory chronic lymphocytic leukemia. This study concluded that venetoclax-rituximab treatment was effective for these patients.     Some background Chronic lymphocytic leukemia...

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First-line treatment with ibrutinib – a review

Posted by on Mar 11, 2018 in Leukemia | 0 comments

In a nutshell This study outlined recent evidence on the use of ibrutinib (Imbruvica) for chronic lymphocytic leukemia (CLL). Some background Tyrosine kinase inhibitor therapy is a type of immunotherapy that blocks signals needed for tumors to grow. This includes the Bruton tyrosine kinase inhibitor ibrutinib. Ibrutinib blocks a signal that keeps the...

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Rituximab, cladribine and cyclophosphamide: Early results of a new treatment combination with and without maintenance therapy

Posted by on Mar 11, 2018 in Leukemia | 0 comments

In a nutshell This study examined a new treatment combination known as RCC followed by rituximab (Rituxan) maintenance therapy for chronic lymphocytic leukemia (CLL). These results support the safety and effectiveness of RCC followed by rituximab maintenance therapy. Risk factors of disease progression were identified. Some background The chemotherapy...

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Promising early results with venetoclax in patients previously treated with idelalisib

Posted by on Jan 18, 2018 in Leukemia | 0 comments

In a nutshell This study examined venetoclax (Venclexta) for patients with chronic lymphocytic leukemia (CLL) previously treated with idelalisib (Zydelig). Researchers reported good response rates and a low rate of side effects for venetoclax after idelalisib. Some background Targeted therapy is the standard treatment of CLL. This includes the...

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Good response rates to venetoclax in patients previously treated with ibrutinib

Posted by on Jan 12, 2018 in Leukemia | 0 comments

In a nutshell This study examined venetoclax (Venclexta) for patients with chronic lymphocytic leukemia (CLL) previously treated with ibrutinib (Imbruvica). Researchers reported good disease control and a low rate of side effects venetoclax after ibrutinib. Some background Targeted therapy is the standard treatment of CLL. This includes the Bruton...

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CAR T-Cells and HIV: What’s the Connection?

CAR T-Cells and HIV: What’s the Connection?

Posted by on Jan 5, 2018 in Blog, Breast cancer, Colorectal cancer, Hodgkin's lymphoma, Leukemia, Lung cancer, Lymphoma, Melanoma, Multiple Myeloma, Non-Hodgkin lymphoma, Prostate cancer | 1 comment

It has taken decades of work for researchers to find ways to activate the immune system to treat cancer (what we now call immuno-oncology or I-O). Much of that work has been poorly funded. Largely, it has been the result of researchers getting experience in other disciplines (like infectious disease) and then transferring that expertise to oncology...

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