In a nutshell This study aimed to investigate the occurrence of infections in children with acute lymphoblastic leukemia or acute myeloid leukemia patients that have completed treatment. This study concluded that infections are a common complication after treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) and acute myeloid...
Read MoreType of leukemia-Acute Lymphoblastic Leukemia (ALL) Posts on Medivizor
Stem cell transplant for blood cancers: mother vs unrelated donors
In a nutshell This study compared the effectiveness of stem cell transplant from a mother donor compared to an unrelated donor in the treatment of cancers of the blood. Researchers found that mother donors could have some better outcomes but with an increased risk of a reaction to the transplant. Some background Cancers of the blood often involve the...
Read MoreDoes cancer and stem cell transplants change taste in children?
In a nutshell This study looked at the changes in the sense of taste of children with cancer and those who received a stem cell transplant. Researchers found that taste changes in these patients were common. Some background Cancer is often treated with powerful drugs or stem cell transplant. These may have strong side effects. In children, it is...
Read MoreUsing steroid medication to prevent stem cell transplant complications in patients with leukemia
In a nutshell This study looked at the effects of using steroid medication to prevent complications after stem cell transplant and improve survival in patients with leukemia. Researchers found that low-dose steroids improved outcomes in these patients. Some background Leukemia is a cancer of the blood-forming tissues such as the bone...
Read MoreSearching for patients with acute lymphoblastic leukemia to test new treatment combination
In a nutshell This trial is comparing the effectiveness of ponatinib (Iclusig) with imatinib (Gleevec) together with low-dose standard chemotherapy for the treatment of patients with acute lymphoblastic leukemia (ALL). The main outcome to be measured is minimal residual disease (low levels of cancer markers in the blood). This study will...
Read MoreDo ACE inhibitors help with anthracycline-induced cardiotoxicity in leukemia and lymphoma?
In a nutshell This study aimed to investigate if enalapril influences anthracycline-induced cardiotoxicity in children with leukemia and lymphoma. This study concluded that enalapril has a role in reducing anthracycline-induced cardiotoxicity in these patients. Some background Anthracyclines are a class of chemotherapy drugs that can be used for...
Read MoreUse of specific T-cells in the treatment of ALL
In a nutshell This study looked at the use of specific T-cells to treat acute lymphoblastic leukemia. Researchers found that using these cells was effective in the treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) is a type of cancer of the bone marrow. This can lead to abnormal cells in the immune system. It is often...
Read MoreStem cell transplantation from the umbilical cord reduces the return of unresponsive acute leukemia
In a nutshell This study looked at the safety and effectiveness of using stem cells from the umbilical cord to reduce the return of disease in acute leukemia. Researchers found that stem cells from the umbilical cord were more effective than stem cells from other areas in the treatment of acute leukemia. Some background Refractory acute leukemia (rAL)...
Read MoreTreatment plans for children with Philadelphia chromosome positive ALL
In a nutshell This study aimed to assess treatment plans and outcomes in children with acute lymphoblastic leukemia and genetic abnormalities in the Philadelphia chromosome (Ph-positive). The study concluded that adding imatinib (Gleevec) to intensive chemotherapy may be an effective treatment for these patients. Some background Acute lymphoblastic...
Read MoreFactors associated with longer hospital stay in children with high-risk ALL
In a nutshell This study aimed to identify risk factors leading to a longer hospital stay in children being treated with chemotherapy for high-risk acute lymphoblastic leukemia (ALL). The study found that a high amount of young patients treated for high-risk ALL experienced a longer hospital stay. Some background Acute lymphoblastic leukemia...
Read MoreThe safety of blinatumomab in the treatment of ALL
In a nutshell This study looked at the safety and effectiveness of blinatumomab (Blincyto) compared with standard chemotherapy in the treatment of acute lymphoblastic leukemia (ALL). The study found that blinatumomab was a safe and effective treatment option compared to chemotherapy in patients with ALL. Some background Acute lymphoblastic leukemia is...
Read MoreDoes graft versus host disease affect relapse and survival rates after a stem cell transplant in childhood leukemia?
In a nutshell This study examined the effect of graft versus host disease on relapse rates in children with acute leukemia. This study concluded that graft versus host disease may protect against relapse, but they did not see an effect on survival. Some background One complication following an allogeneic stem cell transplant (transplant using donor...
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