Treatment(s) now being considered-Surgical excision Posts on Medivizor

Evaluating the effectiveness and safety of immune checkpoint inhibitors given before surgery for the treatment of resectable mucosal melanoma.

Posted by Medivizor on Oct 22, 2023 in Melanoma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of immune checkpoint inhibitors (ICIs) given before surgery for the treatment of patients with resectable mucosal melanoma. The data showed that ICIs given before surgery were effective with manageable side effects for these patients. Some background Melanoma is an aggressive type of skin...

Evaluating the outcomes of current therapies after surgery for patients with stage III melanoma who did not undergo complete lymph node dissection.

Posted by Medivizor on Oct 31, 2021 in Melanoma | 0 comments

In a nutshell This study evaluated the outcomes of immune and molecular targeted therapies after surgery for patients with stage III melanoma who did not undergo complete lymph node dissection. The data showed that the immune and targeted therapies after surgery were associated with increased survival without metastasis among these patients. Some...

Safety and effectiveness of different therapies after surgery for patients with resected melanoma.

Posted by Medivizor on Jan 31, 2021 in Melanoma | 0 comments

In a nutshell This study compared how safe and effective are different therapies after surgery in patients with melanoma. This study showed that nivolumab had the best outcome for patients with melanoma following surgery. Some background Melanoma is a type of skin cancer. First line therapy for melanoma involves surgery to...

Comparing nivolumab and ipilimumab treatment after surgery for advanced melanoma

Posted by Medivizor on Oct 11, 2020 in Melanoma | 0 comments

In a nutshell This study compared nivolumab (Opdivo) and ipilimumab (Yervoy) for treating advanced melanoma that has been surgically removed. They found that patients treated with nivolumab survived cancer-free for longer than patients treated with ipilimumab. Some background Melanoma which has spread to the lymph nodes or other organs is...

Evaluating the safety of smaller excision margins for thick melanomas

Posted by Medivizor on Sep 13, 2019 in Melanoma | 0 comments

In a nutshell This study evaluated the effectiveness of 2 cm versus 4 cm excision margins for patients with thick melanomas on the surface of the skin (cutaneous). This study concluded that a 2-cm excision margin was safe for these patients. Some background The primary treatment for all stages of melanoma is surgery to remove the tumor. This involves...

Searching for patients with high-risk melanoma to test pembrolizumab before and after surgery

Posted by Medivizor on Feb 26, 2019 in Melanoma | 0 comments

In a nutshell This trial aims to test the effectiveness of pembrolizumab (Keytruda) before and after surgery in patients with high-risk melanoma. The main outcome that will be measured will be survival without cancer-related events. The details Pembrolizumab is an anti-cancer medication that targets the immune system. It helps the immune system...

Optimal surgery margins in stage 2 melanomas

Posted by Medivizor on Nov 14, 2016 in Melanoma | 0 comments

In a nutshell This study investigated the safe margin (the tissue removed around the tumor during surgery) for stage 2 melanomas (tumors with 1-2 mm in thickness). Researchers suggested that the safe margin during melanoma surgery is between 8 and 16 mm. Some background The standard treatment for patients with stage 2 melanomas (tumor...

Treatment with vemurafenib before surgery in metastatic melanoma

Posted by Medivizor on Feb 29, 2016 in Melanoma | 0 comments

In a nutshell The authors assessed the effect of vemurafenib (Zelboraf) in metastatic (spread to other areas of the body) melanoma patients prior to surgery. The authors found that surgery to remove metastatic tumors is safe and effective during or just after treatment with vemurafenib. Some background In advanced melanoma (stages 3 to...

Relapse and survival in acral and nonacral melanoma: a comparison

Posted by Medivizor on Aug 21, 2015 in Melanoma | 0 comments

In a nutshell The authors analyzed the effectiveness of standard melanoma treatments in the management of acral melanoma (a type of skin cancer affecting specific parts of a body). Some background Acral melanoma affects the skin of the limbs, ears, fingers or nails. The occurrence of acral melanoma is most common in people with darker...

Role of additional treatment with radiotherapy in desmoplastic melanoma

Posted by Medivizor on Jul 13, 2015 in Melanoma | 0 comments

In a nutshell The authors analyzed the effectiveness of radiotherapy after surgery in desmoplastic melanoma- a rare kind of skin cancer. Some background Desmoplastic melanoma is a rare form of skin cancer in which the cancer cells are surrounded by fibrous tissues (eg; tissues that make up ligaments, tendons or nerves). Local...

Long-term follow up and survival after melanoma relapse

Posted by Medivizor on Jul 12, 2015 in Melanoma | 0 comments

In a nutshell The authors analyzed the factors that predict the return of melanoma (recurrence) and the survival of recurrent melanoma patients following a negative diagnostic report. Some background One of the most important factors that predict the possibility of melanoma recurrence is the status of sentinel lymph node (SLN). SLN is...

Safe surgical margin and management of lymph nodes in skin melanoma

Posted by Medivizor on Jun 3, 2015 in Melanoma | 0 comments

In a nutshell The objective of this study was to determine the safe surgical margin in skin melanoma (2-4 mm thickness) and provide guidelines on the management of affected adjacent lymph nodes. Some background Melanoma is a type of cancer that starts in color-producing cells of the skin. It can grow deep into the inner layers of skin and...

Treatment(s) now being considered-Surgical excision Posts on Medivizor

Evaluating the effectiveness and safety of immune checkpoint inhibitors given before surgery for the treatment of resectable mucosal melanoma.

Evaluating the outcomes of current therapies after surgery for patients with stage III melanoma who did not undergo complete lymph node dissection.

Safety and effectiveness of different therapies after surgery for patients with resected melanoma.

Comparing nivolumab and ipilimumab treatment after surgery for advanced melanoma

Evaluating the safety of smaller excision margins for thick melanomas

Searching for patients with high-risk melanoma to test pembrolizumab before and after surgery

Optimal surgery margins in stage 2 melanomas

Treatment with vemurafenib before surgery in metastatic melanoma

Relapse and survival in acral and nonacral melanoma: a comparison

Role of additional treatment with radiotherapy in desmoplastic melanoma

Long-term follow up and survival after melanoma relapse

Safe surgical margin and management of lymph nodes in skin melanoma

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