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Treatment(s) now being considered-Surgery Posts on Medivizor

Evaluating the safety and efficacy of adding oxliplatin to fluoropyrimidine chemoradiotherapy before surgery in patients with locally advanced rectal cancer

Evaluating the safety and efficacy of adding oxliplatin to fluoropyrimidine chemoradiotherapy before surgery in patients with locally advanced rectal cancer

Posted by on May 31, 2013 in Colorectal cancer | 0 comments

In a nutshell This review compared the efficacy and risks associated with adding oxaliplatin (OX) to fluoropyimidine (FU) chemoradiotherapy (CRT) before surgery in patients with locally advanced rectal cancer (LARC).  Some background In LARC, the cancer has grown from the rectum (the lowest part of the large bowel) into surrounding...

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Evaluating the benefits of laparoscopy in determining the extent of peritoneal carcinomatosis for patients with colorectal cancer

Evaluating the benefits of laparoscopy in determining the extent of peritoneal carcinomatosis for patients with colorectal cancer

Posted by on May 13, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated whether the use of a minimally invasive diagnostic technique called laparoscopy before surgery to treat peritoneal carcinomatosis improves the selection of patients who can benefit the most from treatment. The authors of the study found that laparoscopy can be used to select patients for whom surgery may be a...

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Factors that influence long term survival in patients with lung metastases from colorectal cancer

Factors that influence long term survival in patients with lung metastases from colorectal cancer

Posted by on May 8, 2013 in Colorectal cancer | 0 comments

In a nutshell This article looks at results from 8 clinical studies where patients had surgery to remove lung metastases. Using patient data from these studies, the authors identified risk factors which can predict the 5 year survival rate. Some background Oligometastasis defines the spread of a primary cancer (in this case colorectal cancer) to a...

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Can a scoring system called a nomogram help develop a treatment program that is individual to each patient?

Can a scoring system called a nomogram help develop a treatment program that is individual to each patient?

Posted by on May 3, 2013 in Colorectal cancer | 0 comments

In a nutshell This article is a short editorial describing how the use of a “nomogram” (a predictive tool based on a points system) could provide a doctor and patient with possible outcomes if different treatment options are selected. Some background The current method of choosing treatment for patients with rectal cancer is fairly...

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Preoperative Magnetic Resonance Imaging can predict good outcomes for rectal cancer patients treated with surgery alone

Preoperative Magnetic Resonance Imaging can predict good outcomes for rectal cancer patients treated with surgery alone

Posted by on Mar 13, 2013 in Colorectal cancer | 0 comments

In a nutshell The present study examined the survival rate of rectal cancer (RC) patients treated with surgery alone, based on preoperative Magnetic Resonance Imaging (MRI) staging predictive of a good prognosis. Some background RC is staged according to how far the cancer has spread through the walls of the rectum (the final section of...

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A genetic profile which identifies patients who will respond to preoperative chemoradiation for rectal cancer

A genetic profile which identifies patients who will respond to preoperative chemoradiation for rectal cancer

Posted by on Mar 7, 2013 in Colorectal cancer | 0 comments

In a nutshell This study looks at the treatment of locally advanced rectal cancer with chemoradiation prior to surgery, and if there are variations in the cancer genes which make some more sensitive to this treatment than others. They find that changes in three individual genes made cancers less sensitive to chemoradiation, and may be a useful...

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Comparison of two surgical techniques for the treatment of pseudomyxoma peritonei

Comparison of two surgical techniques for the treatment of pseudomyxoma peritonei

Posted by on Mar 4, 2013 in Colorectal cancer | 1 comment

In a nutshell The present study compared the efficacy of two surgical techniques to treat pseudomyxoma peritonei (PMP): debulking and cytoreduction. Cytoreductive surgery achieved better surgical results and yielded higher 3- and 5-year survival rates, compared with debulking. Some background PMP is a rare condition caused by the production of...

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The impact of radiotherapy protocol on quality of life in patients with operable rectal cancer

The impact of radiotherapy protocol on quality of life in patients with operable rectal cancer

Posted by on Mar 3, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated the long-term quality of life of patients with rectal cancer, treated with either a short course of radiation before surgery, or postoperative chemo-radiation. Patients treated with pre-operative radiation reported worse sexual- and bowel-related functional outcomes.   Some background In patients with...

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What is the preferred duration of post-operative chemotherapy for stage II and III colorectal cancer?

What is the preferred duration of post-operative chemotherapy for stage II and III colorectal cancer?

Posted by on Feb 24, 2013 in Colorectal cancer | 0 comments

Colorectal cancer (CRC) is one of the main causes of cancer related deaths. Patients diagnosed with CRC are treated with surgery to remove the tumor and affected tissue. If the tumor affects the entire thickness of the colon or rectal wall it is referred to as being stage II; if the local lymph nodes are also affected the cancer is referred to as being a...

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The use of systemic chemotherapy for patients with poorly differentiated and signet cell adenocarcinoma of the appendix

The use of systemic chemotherapy for patients with poorly differentiated and signet cell adenocarcinoma of the appendix

Posted by on Feb 24, 2013 in Colorectal cancer | 0 comments

In a nutshell The present study evaluated the effects of systemic chemotherapy and cytoreductive surgery (CRS) on survival in patients with aggressive types of cancer of the appendix (poorly differentiated and signet ring cell adenocarcinoma). The main findings were that systemic chemotherapy appears to be a viable treatment option for these types of...

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