In a nutshell This paper studied the effect of adjuvant therapy (treatment given after surgery) in patients who had a complete response to therapy with trastuzumab (Herceptin) before surgery. Some background Neoadjuvant systemic therapy is treatment used to decrease the size of the tumour before surgery. An example of treatment...
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In a nutshell This paper reviewed whether or not using omentum in breast surgery is safe. Some background The omentum is a fatty tissue that covers the intestines. It can be used in breast surgery, to treat deformities of breasts, for aesthetic breast procedures and for partial breast reconstruction (surgery to rebuild the breast after it is...
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In a nutshell This paper studied the outcomes of a skin-sparing mastectomy procedure. Some background More and more people are undergoing skin-sparing mastectomies. This is a treatment for breast cancer where breast tissue is removed, but the overlying skin is preserved as much as possible. It also allows for immediate breast...
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In a nutshell The study examined whether radiation therapy increased the risk of implant failure in women undergoing immediate breast reconstruction following mastectomy. Some background Treatment for breast cancer generally includes a combination of surgery to remove either the tumor or the full breast (mastectomy), radiation, and chemotherapy....
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In a nutshell In this study, researchers examined whether breast cancer patients who chose to have preventive removal of both breasts (bilateral mastectomy or BM) experience more post-surgery complications than patients who have removed only the cancer-affected breast (unilateral mastectomy or UM). Some background Most women with early breast...
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In a nutshell This study questioned the benefit of adding chemotherapy to postoperative hormonal treatment in the case of lobular breast cancer. Their findings were that chemotherapy seems to offer no additional beneficial effects in women with lobular breast cancer receiving hormonal therapy. Some background There are two main types of breast...
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In a nutshell The present study compared the long-term efficacy and safety of different adjuvant chemotherapy regimens for breast cancer. Main results: chemotherapy clearly provides survival benefits; the higher the dosage, the higher the survival rates, despite more toxicity. Some background Many women with early stage breast cancer receive...
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In a nutshell This study compared the benefits of chemotherapy according to hormone receptor status. The main findings were: In cancers without hormone receptors, the benefits of adding chemotherapy were significant; In cancers with hormone receptors, chemotherapy only offered modest improvement. Some background Some...
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In a nutshell This paper reviews available options for having children after cancer treatment. The main conclusion is that sperm, egg and embryo preservation techniques can help young women have children after breast cancer treatment. Alternative options, such as ovarian tissue preservation, are also being developed. Some background...
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