In a nutshell This study examined the evidence for combining androgen deprivation therapy (ADT) with radiation therapy for the treatment of high-risk localized prostate cancer. Authors concluded that the combined therapy approach was associated with a survival advantage for intermediate- and high-risk patients. Some background ADT is a type...
Read MoreIn a nutshell This study examined the effect of combined radiation and hormone therapy on long-term fatigue. Researchers reported severe fatigue during and up to 4 years after treatment. Men with increased cancer markers and symptoms were more likely to report higher fatigue levels. Some background Radiation therapy and hormone therapy are often...
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In a nutshell This study examined the benefit of combining radiation therapy with androgen deprivation therapy (ADT) in older men and in men with aggressive cancer cells. Researchers reported reduced mortality risks with combination therapy in all groups studied. Some background Radiation therapy is a common treatment for localized...
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In a nutshell This study looked at the safety and effectiveness of a type of chemoradiotherapy following surgery for rectal cancer. Some background Radiation therapy uses high-energy radiation to kill cancer cells by damaging their DNA. Advanced radiation treatments such as three-dimensional conformal radiotherapy (3D-CRT) and...
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In a nutshell This study looked at the risks of lung cancer recurrence (return after treatment) and mortality rates following recurrence. Some background Treatment for early-stage lung cancer (cancer that has not spread to other areas) typically involves a combination of surgery, chemotherapy and radiation. Patients usually receive...
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In a nutshell The authors aimed to determine whether psychological therapy could relieve patients with fatigue (extreme tiredness) who are undergoing breast cancer radiation (uses high energy radiation to kill cancer cells by damaging their DNA) treatment. Some background Radiation is a treatment that has been proven to increase a patient’s...
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In a nutshell The authors evaluated the effectiveness of radiation therapy after surgery in the management of desmoplastic melanoma (a rare kind of skin cancer). Some background Desmoplastic melanoma is a rare form of skin cancer where the cancer cells are surrounded by fibrous tissues (e.g. tissues that make up ligaments, tendons or...
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In a nutshell The authors determined the effect of radiotherapy as an additional treatment, in patients with node-positive prostate cancer. Some background Radiotherapy is a common treatment used in prostate cancer. It involves directing a beam of radiation at the tumor site to kill cancer cells with minimal damage to...
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In a nutshell This study looked at the survival of patients with advanced rectal cancer when treated with chemotherapy either before or after chemoradiation and surgery. Some background A common treatment option for rectal cancer is a combination of chemotherapy and radiation therapy (chemoradiation) followed by surgery. Further...
Read MoreIn a nutshell This phase I/II trial aims to determine the safety of administering shorter courses of radiation over a shorter period of time to patients who have had their prostate removed. The main outcome to be investigated is dose safety and toxicity in patients and to determine quality of life benefits. The details Radiation therapy...
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In a nutshell The authors aimed to determine the advantage of neo-adjuvant (treatment given before surgery) therapies in terms of eligibility for certain surgeries. Some background Neo-adjuvant chemotherapy (NAC) is often provided to patients prior to surgery in an attempt to first shrink the tumor. This type of treatment is known to increase the...
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In a nutshell The authors evaluated the factors associated with improved outcomes in patients with lung cancer treated with stereotactic body radiotherapy (SBRT). Some background Stereotactic body radiotherapy (SBRT) is a type of radiotherapy used to treat lung cancer. With SBRT, a beam of radiation is focused directly on the tumor,...
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