In a nutshell This study examined the effect of pre-surgical chemotherapy without radiotherapy in stage II/III rectal cancer. The study showed that combined targeted chemotherapy was effective in these patients. Some background Rectal cancer is a cancer of the end part of the digestive system. In stage II and III, the cancer has begun to...
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Stereotactic body radiotherapy in oligorecurrent prostate cancer
In a nutshell The authors aimed to determine the effect of tumor-directed stereotactic body radiotherapy in prostate cancer patients with oligometastases. The authors concluded that tumor-directed stereotactic body radiotherapy was a useful treatment for both oligorecurrent and oligoprogressive castration-resistant prostate cancer. Some...
Read MoreComparison between low and high dose brachytherapy followed by radiation in prostate cancer
In a nutshell The authors aimed to compare urinary symptoms in men with localized prostate cancer treated with either low-dose or high-dose rate brachytherapy in combination with radiation therapy. The authors concluded the both low-dose and high-dose brachytherapy with IMRT was safe and well-tolerated by patients. However, it took longer to recover...
Read MoreLong term follow-up study of reduced intensity treatments for early stage Hodgkin lymphoma
In a nutshell This study provided a long-term follow-up of patients diagnosed with early-stage Hodgkin lymphoma. The study concluded that current strategies for reduced intensity treatment of early-stage Hodgkin lymphoma are generally safe and effective. Some background Hodgkin lymphoma (HL) is generally considered a curable disease....
Read MoreCarbon-ion radiation therapy is a safe treatment option for head and neck melanomas
In a nutshell This study investigated the effectiveness and safety of carbon-ion radiation therapy (CRT) for mucosal melanoma of the head and neck. Researchers suggested that CRT is an important treatment option for these patients. Some background Mucosal head and neck melanomas account for roughly 1% of all melanomas. However, is typically...
Read MoreLong-term effects of stereotactic ablative radiotherapy for patients with NSCLC
In a nutshell The authors examined the long-term effects of stereotactic ablative radiotherapy (SABR) in treating patients with stage 1 non-small-cell lung cancer (NSCLC). They concluded that SABR is both safe and effective in the long-term. Some background SABR is a type of radiation used to treat inoperable early stage NSCLC. Studies have shown...
Read MoreHow radiotherapy for breast cancer influences long-term the risk of lung cancer and heart disease
In a nutshell This study investigated the results of previous trials to determine the effects of breast cancer (BC) radiotherapy (RT) on the long-term risk of developing other health conditions later in life. This study determined that for long-term smokers, the future health risks associated with RT may outweigh the benefits. Some background RT...
Read MoreThe impact of co-morbidities on post-stem cell transplant survival in patients over 50
In a nutshell This study compared the survival outcomes of two different age groups of relapsed and refractory Hodgkin lymphoma patients. The authors concluded that co-morbidities, not age, reduced survival rates after stem-cell surgery. Some background Hodgkin lymphoma (HL) is a type of cancer of the lymph system. It is generally highly...
Read MoreEffects of brentuximab-vedotin therapy in relapsed and refractory Hodgkin lymphoma
In a nutshell This study evaluated the effectiveness of brentuximab-vedotin therapy in relapsed- and refractory Hodgkin lymphoma patients. The authors concluded that the treatment was safe and effective. Some background Some Hodgkin lymphoma patients are either unresponsive to treatment (refractory disease), or relapse soon...
Read MoreThe impact of cancer-related fatigue on Hodgkin lymphoma patients and survivors
In a nutshell This study determined the impact of cancer-related fatigue on Hodgkin-Lymphoma patients and survivors. The authors concluded that fatigue particularly affected social integration. Some background Hodgkin-Lymphoma (HL) patients and survivors can experience persistent cancer-related fatigue. Reports of fatigue occur 2.5 to 3...
Read MoreCan radiation and hormone therapy after surgery improve prostate cancer survival rates?
In a nutshell The aim of this study was to determine whether radiation therapy in combination with hormonal therapy improved survival in men with prostate cancer that has spread to the lymph nodes after surgery. Researchers concluded that patients treated with radiation therapy and hormone therapy had a significantly higher survival rate compared to...
Read MoreBreast-conserving therapy versus mastectomy in N2 stage breast cancer
In a nutshell This study compared long-term survival following breast conserving surgery or mastectomy in patients with T1-2N2 breast cancer. The authors concluded that breast conserving surgery plus radiation was as effective as mastectomy and radiation in these patients. Some background Breast cancer is staged depending on the severity and...
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