In a nutshell This study compared in vitro maturation (IVM) to double ovarian stimulation (DuoStim) for women expected to have a poor outcome from in vitro fertilization (IVF). It found that both methods increased the number of eggs compared to standard IVF, and that DuoStim may be more effective. Some background The first step of the infertility...
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In a nutshell This study compared the effectiveness and safety of progestins to gonadotrophin-releasing hormone (GnRH) medications for women trying to conceive. The results showed that progestins were as effective and safe as GRH medications and could be used as a cheaper alternative. Some background For women using medical assistance to...
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In a nutshell This study compared human menopausal gonadotropin (hMG) to follicle-stimulating hormone (FSH) prior to intracytoplasmic sperm injection (ICSI) for patients predicted to have a strong ovarian response. It found that both types of gonadotropin hormone were effective, but that hMG had fewer side effects and miscarriages. Some background...
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In a nutshell This study analyzed treatment options for patients with a poor ovarian response (POR) to ovarian stimulation procedures for infertility. They found that supplements with DHEA and coenzyme Q10 (CoQ10) improved pregnancy rates in these women. Some background Controlled ovarian stimulation (COS) is the first part of assisted...
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In a nutshell This study compared two methods to induce ovulation (egg release) in women with polycystic ovarian syndrome (PCOS). This study found that letrozole (Femara) and menotropin (Humegon) resulted in similar pregnancy rates, but letrozole had fewer side effects. Some background PCOS is a common cause of infertility in...
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In a nutshell This study compared minimal ovarian stimulation (MOS) to conventional ovarian stimulation (COS) in women undergoing fertility treatment. They found that MOS resulted in greater numbers of good-quality embryos and oocytes (eggs) in these women. Some background During fertility treatment, women undergo controlled ovarian...
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In a nutshell This study investigated if progestin-primed ovarian stimulation (PPOS) is associated with infant birth defects. They found that PPOS is not associated with negative outcomes in infants. Some background Assisted reproductive techniques (ART) include in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). In order to...
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In a nutshell This study investigated if myo-inositol (MI) reduces the amount of gonadotrophins (GTs) needed for ovarian stimulation and the length of treatment in women undergoing in vitro fertilization (IVF). The results showed that MI reduced the amount of GTs needed and the duration of fertility treatment in these women. Some background...
Read MoreIn a nutshell This study investigated the effects of kisseptin on the risk of ovarian hyperstimulation syndrome (OHSS) in high-risk women undergoing fertility treatment. The authors suggested that kisseptin treatment resulted in lower rates of OHSS compared to standard treatment. Some background One of the first procedures for the...
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In a nutshell This paper studied the outcome after use of GnRH antagonists and cryopreservation of embryos in women who were at high risk of ovarian hyperstimulation syndrome. Use of GnRH antagonists was effective in achieving high levels of birth rate. Some background In-vitro fertilization is a procedure whereby the egg is fertilized by the...
Read MoreIn a nutshell This paper studied whether uterine fibroids can affect pregnancy outcomes following ovarian stimulation with intrauterine insemination. Authors reported no differences in live birth rates in women with fibroids and those without fibroids. Some background Uterine fibroids are non-cancerous growths around the uterus. Studies have been...
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In a nutshell This paper studied whether calcium could reduce the risk of ovarian hyperstimulation syndrome in women undergoing in-vitro fertilisation (IVF). Authors concluded that an infusion of calcium significantly reduced the rate of ovarian hyperstimulation in women at high risk. Some background In-vitro fertilisation (IVF) is a procedure...
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