In a nutshell This study investigated the impact of starting chemotherapy treatment immediately after colon cancer surgery. Researchers suggested that this option is safe. Some background Colorectal cancer is the third most common cancer worldwide. The standard treatment is surgery and chemotherapy. However, colon cancer surgery is associated with a...
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In a nutshell This study investigated the benefit of anthracyclines (ATCs) in early breast cancer. They found that this treatment was an effective treatment in patients with early breast cancer. Some background Breast cancer (BC) is one of the most common cancers. Early BC is usually treated with surgery to remove the tumor....
Read MoreIn a nutshell This study investigated if patients with Hodgkin lymphoma (HL) found in the bones have worse outcomes than patients with HL in the lymph nodes. It was found that having bone HL did not reduce survival of patients. Some background Many patients with HL are cured by treatment. After 5 years, almost 86% of patients survive. When...
Read MoreIn a nutshell This study investigated the relationship between lymphocyte (a type of white blood cells) counts and treatment outcomes for patients with rectal cancer. Researchers suggested that lymphocyte count reduction may be caused by rectal cancer treatment and is associated with better tumor response. Some background Colorectal cancer is the...
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In a nutshell This study wanted to see how well two medications worked in treating advanced triple negative breast cancer, atezolizumab (Tecentriq) and nab-paclitaxcel (Abraxane). The study found that using these two medications together improved survival in these patients. Some background Triple-negative breast cancer (TNBC) is breast cancer...
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In a nutshell This study compared the effectiveness of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) with other treatment options in patients with colorectal cancer (CRC) and peritoneal metastasis (PM; when cancer spreads to the abdominal lining). Researchers suggested that CRS + HIPEC brings the greatest...
Read MoreIn a nutshell This study looked at a combination of irinotecan (Camptosar) and platinum-based drugs, for treating patients with extensive-stage small cell lung cancer. The authors concluded that this combination has the potential to improve the outcomes for these patients. Some background Extensive stage small-cell lung cancer (ES-SCLC) is...
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In a nutshell This study evaluated the effectiveness of fluorouracil (Adrucil) chemotherapy after surgery in patients with non-small-cell lung cancer (NSCLC). The authors concluded that treatment with fluorouracil resulted in prolonged recurrence-free survival compared to standard chemotherapy regimens. Some background Adjuvant therapy is given in...
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In a nutshell This study investigated the development of hypothyroidism in patients with Hodgkin lymphoma after chemoradiation therapy. Patients were more likely to develop hypothyroidism after intensity modulated radiation therapy than after 3-dimensional conformal radiation therapy. Some background Patients with Hodgkin lymphoma (HL) are commonly...
Read MoreIn a nutshell This trial is examining the effectiveness of atezolizumab (Tecentriq) when used with chemotherapy in patients with inoperable, recurrent triple-negative breast cancer. The main outcome to be measured will be the overall survival (time from treatment until death from any cause) of participants. The...
Read MoreIn a nutshell This trial is examining the effectiveness of chemotherapy and atezolizumab (Tecentriq), given before surgery, for triple negative breast cancer. The main outcomes to be measured will be response in the breast tissue and lymph nodes and survival. The details Triple negative breast cancer is not dependent on the HER2 receptors or...
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In a nutshell This study aimed to discover the optimal timing of hormone therapies in combination with androgen-deprivation therapy (ADT) for patients with metastatic hormone-sensitive prostate cancer. This study found that treatment with a second hormone therapy after prostate cancer becomes immune to hormone treatment is associated...
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