In a nutshell The aim of this study was to evaluate the impact of adding oxaliplatin (Eloxatin) to the chemotherapy regimen tegafur uracil (UFT)/leucovorin (LV; folinic acid) for patients that had surgery for colorectal cancer (CRC). The study found that the addition of oxaliplatin to UFT/LV improved patient outcomes. Some background CRC can...
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In a nutshell This study investigated if reducing therapy duration could reduce side effects in patients but still be effective in patients with stage II colorectal cancer (CRC). This study showed that in certain patients a 3-month treatment duration can be considered. Some background Patients with colorectal cancer (CRC) can be treated...
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In a nutshell This study compared 3 and 6 months of oxaliplatin (Eloxatin)-based chemotherapy in stage 2 colon cancer. Researchers suggested that the 3-month treatment might be a good and safer option for these patients. Some background Colorectal cancer is the third most common cancer diagnosed in both men and women in the US. Chemotherapy after...
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In a nutshell This study reviewed the effect of follow-up programs on the survival of patients with colorectal cancer. Researchers suggested that intense follow-up programs do not improve the survival of these patients. Some background Colorectal cancer is a commonly diagnosed cancer in the US. Two in three patients will present with the possibly...
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In a nutshell This study investigated the role of oxaliplatin (Eloxatin) in treating patients with rectal cancer after surgery. Researchers suggested that this drug may be a good option in the treatment of rectal cancer. Some background Chemotherapy is one of the standard treatments for rectal cancer. It usually consists of...
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In a nutshell This study investigated the effectiveness of surgery followed by chemotherapy without chemoradiotherapy (CRT) before surgery to treat rectal cancer. Researchers suggested that this treatment improves the outcomes of these patients. Some background Colorectal cancer is the third most common cancer worldwide. The standard...
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In a nutshell This study investigated the impact of chemotherapy after surgery (CAS) in patients with rectal cancer who had a complete response to chemotherapy before surgery. Researchers suggested that the routine use of CAS should not be recommended in these patients. Some background Colorectal cancer is one of the most common cancer...
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In a nutshell This trial is comparing the effectiveness and toxicity of ABT-165 or bevacizumab (Avastin) plus FOLFIRI (irinotecan, leucovorin, fluorouracil) chemotherapy in patients with metastatic (spread to other parts of the body) colorectal cancer. The main outcome to be measured will be tumor response and survival without cancer...
Read MoreIn a nutshell This trial is comparing the effectiveness of a new therapy, bb2121, to commonly used combinations of drugs for relapsing/refractory (unresponsive) multiple myeloma (RRMM). The main outcome to be measured is the time from the start of treatment until cancer worsens. The details Many patients are cured with standard treatments, such as...
Read MoreIn a nutshell This study investigated the use of chemotherapy after surgery in elderly patients with stage 2 and 3 colon cancer. Researchers suggested that chemotherapy after surgery improves outcomes in patients with stage 3 colon cancer. Some background Life expectancy in the Western countries has increased. Colorectal cancer is diagnosed most...
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In a nutshell This study investigated the effectiveness of a 3-month oxaliplatin-based chemotherapy treatment after surgery in patients with stage 3 colon cancer. Researchers suggested 6-months of treatment is associated with better outcomes. Some background The current standard treatment for stage 3 colon cancer patients is surgery followed by...
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In a nutshell This study investigated the optimal time to start chemotherapy after colon surgery. Researchers suggested that patients should start chemotherapy within 8 weeks after surgery. Some background The recommended treatment for stage 3 colon cancer is surgery followed by chemotherapy. This reduces the risk of recurrence (when the cancer comes...
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