In a nutshell The authors determined how positive surgical margins increased the risk of prostate cancer return in patients following prostate surgery. Some background Prostate surgery is a common treatment in prostate cancer that involves surgically removing the prostate gland. Surgical margin refers to the visible normal tissue...
Read MoreIn a nutshell This phase I/II trial aims to determine the safety of administering shorter courses of radiation over a shorter period of time to patients who have had their prostate removed. The main outcome to be investigated is dose safety and toxicity in patients and to determine quality of life benefits. The details Radiation therapy...
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In a nutshell The authors determined whether hormone therapy had a negative impact on mental function (cognitive performance) in prostate cancer patients. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones involved in prostate cancer, such as testosterone. Some studies have...
Read MoreIn a nutshell The authors determined the factors that predict cancer recurrence (return of cancer) and how they can affect overall survival in prostate cancer patients. Some background One of the most common treatments for prostate cancer is the surgical removal of the prostate gland (prostate surgery). However, 10% of patients who...
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In a nutshell The authors aimed to determine whether solifenacin succinate (VESIcare) could be used to treat voiding dysfunction in patients who underwent prostate surgery. Some background Prostate surgery involves surgically removing the prostate gland in prostate cancer patients. In some cases patients may experience side effects such...
Read MoreIn a nutshell The authors aimed to determine the effect of phosphodiesterase type 5 inhibitors on penile functioning following prostate surgery. Some background Prostate surgery is a form of treatment that involves surgically removing the prostate gland which can cause erectile dysfunction in some patients. Phosphodiesterase type 5...
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In a nutshell The authors aimed to determine the effect of phosphodiesterase type 5 inhibitors on biochemical recurrence following prostate surgery. Some background Prostate surgery is a form of treatment that involves surgically removing the prostate gland which can cause erectile dysfunction in some patients. Phosphodiesterase type 5 inhibitors...
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In a nutshell The authors aimed to determine the effect of early and delayed radiation treatment on patient outcome following prostate surgery. Some background Prostate surgery involves surgically removing the prostate gland in patients with prostate cancer. Radiation therapy involves directing a beam of radiation at the tumor site in order...
Read MoreIn a nutshell The authors aimed to determine whether abiraterone acetate (Zytiga) can be used to stop tumor activity in castration-resistant prostate cancer in patients with and without PTEN protein function. Some background PTEN is a protein that controls cell processes like survival, replication and movement within the body. It has recently...
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In a nutshell The authors aimed to determine whether the biopsy-based Genomic Prostate Score test could predict cancer recurrence in a racially diverse group after radical prostatectomy. Some background Active surveillance is an option taken in patients with low-risk prostate cancer (confined to the prostate) which involves no physical treatment,...
Read MoreIn a nutshell The authors analysed the effect of positive surgical margins on cancer-specific survival. Some background When tumors are removed, typically extra tissue around the tumor is also removed to increase the likelihood of removing all the cancer cells. Estimating surgical margins involves examining this extra tissue after or during...
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In a nutshell The authors evaluated the prevalence and management of urethral blockage following certain cancer treatments. Some background Urethral stenosis is a medical condition characterized by a blockage in the urethra, the tube which drains fluid from the bladder to the outside of the body. The point of the blockage is referred to...
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