In a nutshell This trial is examining the effectiveness of radiation therapy with or without apalutamide (Erleada) in the treatment of stage 3-4 prostate cancer. The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in Canada and the United States. The details Radiation therapy uses high energy x-ray...
Read MoreTreatment(s) already received-Radical prostatectomy Posts on Medivizor
Is conventional or hypofractionated radiation therapy better for the treatment of prostate cancer?
In a nutshell This study compared two different types of radiation therapy after prostate surgery for prostate cancer, hypofractionated postprostatectomy radiation therapy (hypoPORT) and conventional postprostatectomy radiation therapy (coPORT). Results showed that hypoPORT may be effective in prostate cancer control and with similar side effects as...
Read MoreCan the ProACT™ surgical implant help with stress urinary incontinence after surgery for prostate cancer?
In a nutshell This study aimed to investigate the use of a surgical implant, in improving quality of life and side-effects of stress urinary incontinence after prostate cancer surgery. This study found that this implant led to significant improvements in quality of life in these patients. Some background Stress urinary incontinence (SUI) is the...
Read MoreSearching for men with high-risk, relapsed prostate cancer to test the use of anti-hormonal medication
In a nutshell This trial is examining the effectiveness of different hormone therapy regimes for patients whose prostate-specific antigen (PSA; a protein elevated in prostate cancer) levels rise after prostate removing surgery. The main outcome to be measured will be the change in PSA levels. The details The best standard treatment for...
Read MoreLooking for patients with prostate cancer who have had a rise in PSA after prostate removal surgery
In a nutshell This trial is examining the effectiveness of different hormone therapy regimes for patients whose prostate specific antigen (PSA; a protein elevated in prostate cancer) levels rise after prostate removing surgery. The main outcome to be measured will be the change in PSA levels. The details The best standard treatment...
Read MoreSide-effects and quality of life changes after robotic prostate surgery
In a nutshell This study aimed to evaluate short and medium-term patient-reported side-effects after robotic prostate surgery. This study found that patient-reported outcome measures evaluating urinary symptoms and health related quality of life do not significantly change after robotic prostate surgery. Some background...
Read MoreCan PET/CT scanning guide radiotherapy treatment in prostate cancer?
In a nutshell This paper studied if a targeted form of radiotherapy could be effective in improving patient outcomes after surgical treatment of prostate cancer. The main finding was that a specific type of radiotherapy using PET scans improved outcomes in these patients. Some background Prostate specific antigen is a chemical in the blood that has...
Read MoreDo side-effects vary between risk groups after treatment for localized prostate cancer?
In a nutshell This study aimed to determine whether differences in side effects reported over time in patients who had surgery or radiotherapy varied by risk group. This study found that for men with low-risk prostate cancer, radiotherapy was associated with higher sexual function scores at 3 years than surgery;...
Read MorePredictive factors of biochemical recurrence after radical prostatectomy for high-risk prostate cancer.
In a nutshell This study aimed to identify risk factors of recurrence after prostatectomy in high risk patients. Patients with more risk factors were more likely to experience disease recurrence at five years. Some background Prostatectomy is a treatment option for prostate cancer. The prostate tumor is surgically removed. There are several risk...
Read MorePSA response after cabazitaxel treatment is associated with improved progression-free survival in men with metastatic castration-resistant prostate cancer.
In a nutshell This study aimed to examine the links between prostate specific antigen (PSA, a protein present in prostate cancer) and survival in patients with metastatic castration-resistant prostate cancer treated with cabazitaxel. This studty concluded that PSA response after cabazitaxel treatment is associated with improved...
Read MoreAn analysis of abiraterone plus prednisone for metastatic castration-resistant prostate cancer
In a nutshell This study aimed to determine which patients benefited most from abiraterone acetate (Zytiga) and prednisone (Deltasone). This study found that overall survival was increased for all patient groups that received this combination. Some background A main treatment option for prostate cancer is androgen deprivation...
Read MoreProteins in the prostate gland can help predict disease recurrence after surgery
In a nutshell This study examined if the collections of proteins in the prostate can predict prostate surgery outcomes. Authors found that protein analysis was a significant predictor of disease recurrence and metastasis (cancer spread) after surgery. Some background Prostate surgery is a first-line treatment option for prostate cancer. It has...
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