In a nutshell This study evaluated the benefits of adding androgen deprivation therapy (ADT) to radiation therapy (RT) and the benefit of extending the duration of ADT in men with localized prostate cancer (PCa). The data showed that the addition of ADT to RT and extending the duration of ADT administered after RT significantly improved the survival...
Read MoreTreatment(s) already received-Radiation Posts on Medivizor
Using focal thermo-ablative therapy for treating oligo-recurrent prostate cancer after radiotherapy.
In a nutshell This study assessed patient responses to focal thermo-ablative therapy (FTA) for oligo-recurrent prostate cancer (PCa) after pelvic radiotherapy. The data suggested that FTA therapy is a good option in these patients. Some background Oligometastatic PCa means that cancer has spread to only a few places (up to 5 metastases). It...
Read MoreDoes radiotherapy increase the risk of heart disease in patients with Hodgkin lymphoma?
In a nutshell This study looked at the 30-year risk of heart disease in patients with Hodgkin lymphoma (HL) treated with radiotherapy. It found that radiotherapy led to a small increase in the risk of death from heart disease or stroke in these patients. Some background HL is often treated with a combination of chemotherapy and...
Read MoreEvaluating pembrolizumab consolidation following chemotherapy and radiation for patients with stage III non-small cell lung cancer.
In a nutshell This trial was carried out to examine the effectiveness of pembrolizumab (Keytruda) consolidation therapy for patients with stage III unresectable non-small cell lung cancer (NSCLC) following a course of chemotherapy and radiation therapy. The authors found that pembrolizumab consolidation improved the outcomes of...
Read MoreSearching for patients with stage III non-small cell lung cancer to trial a biological treatment.
In a nutshell This trial is aiming to examine the effectiveness and safety of atezolizumab (Tecentriq) and tiragolumab compared to durvalumab (Imfinzi) in stage III non-small-cell lung cancer (NSCLC) that cannot be surgically removed and has previously been treated with concurrent (at the same time) platinum-based chemoradiation therapy (CRT)....
Read MoreLooking for patients with stage III non-small cell lung cancer to trial a treatment combination with radiotherapy
In a nutshell This study is looking to examine the effectiveness of durvalumab (Imfinzi) and consolidation stereotactic body radiation therapy (SBRT) after chemoradiation for locally advanced stage III non-small-cell lung cancer (NSCLC). The main outcomes to be measured are the occurrence of side effects and the survival without cancer...
Read MoreComparing cryosurgery and hormonal therapy for locally recurrent prostate cancer after radiotherapy
In a nutshell This study compared local cryosurgery (CRYO) against androgen deprivation therapy (ADT) for the treatment of locally recurring prostate cancer (LRPC). The study found local cryosurgery had a longer overall survival (OS) when compared to ADT. Some background LRPC is cancer that has re-occurred in the prostate gland...
Read MoreOxaliplatin in the treatment of rectal cancer after surgery
In a nutshell This study investigated the role of oxaliplatin (Eloxatin) in treating patients with rectal cancer after surgery. Researchers suggested that this drug may be a good option in the treatment of rectal cancer. Some background Chemotherapy is one of the standard treatments for rectal cancer. It usually consists of...
Read MoreShould additional chemotherapy be added to chemoradiotherapy in patients with inoperable non-small cell lung cancer?
In a nutshell This study examined how effective additional chemotherapy alongside chemo-radiotherapy is in patients with locally advanced non-small cell lung cancer. The study found that additional chemotherapy did not bring survival benefits in these patients. Some background Non-small cell lung cancer (NSCLC) can be difficult to treat. There are a...
Read MoreDoes remission status influence outcomes of SCT for patients with Hodgkin’s lymphoma?
In a nutshell This study evaluated the outcomes of allogeneic stem cell transplantation (SCT) in patients with classical Hodgkin’s lymphoma (CHL) that was refractory (resistant to treatment) or had relapsed. The study found that patients in complete remission (no signs of cancer) when they received the transplant had better outcomes. Some...
Read MoreEvaluating the safety of re-treatment with radium-223
In a nutshell This study aimed to evaluate the safety and effectiveness of radium-223 (Xofigo, formerly known as Alpharadin) in patients with advanced prostate cancer that has spread to the bones and who have had this treatment previously. This study found that re-treatment with radium-223 was well tolerated and with good results. Some background...
Read MoreSearching for patients to try a new therapy for advanced solid tumors.
In a nutshell This study is searching for participants with advanced solid tumors to try a new treatment called repotrectinib (TPX-0005). The main outcomes that will be measured include side effects, the most effective dose and response. This trial is recruiting in the United States and Korea. The details Patients with different genetic mutations...
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