In a nutshell This study looked at etanercept (Enbrel) for women who have had repeated unsuccessful in vitro fertilization (IVF). It found that etanercept led to good pregnancy rates in these patients. Some background The uterus forms a connection between the vagina, which is open to the outside, and the inside of the body. If harmful bacteria...
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In a nutshell This study looked at using the anti-inflammatory progestin dienogest (Visanne) prior to in vitro fertilization (IVF) for patients with endometriosis with a previously failed IVF. It found that dienogest improved IVF outcomes in these women. Some background Endometriosis is a chronic illness in which cells from the lining of the uterus...
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In a nutshell This study looked at the number of days of progesterone treatment before frozen embryo transfer (FET) in hormone replacement cycles. It found that transfers after 7 days of progesterone may miscarry less, but the birth rate was the same as transfers after 6 days of progesterone. Some background In vitro fertilization (IVF) is an...
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In a nutshell This study investigated if cardiovascular function (CVF) is altered by in vitro fertilization (IVF). They found that IVF may cause short-term changes to CVF in women. Some background In vitro fertilization (IVF) is used to treat infertility. The first step of IVF involves harvesting eggs. Women inject hormones to stimulate the...
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In a nutshell This study looked at whether injecting HCG hormone into the womb before embryo transfer improved pregnancy rates. This study concluded that HCG improved pregnancy rates for women with a history of unsuccessful implantation. Some background One cause of infertility is poor implantation of an embryo in the uterus. This occurs when the...
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In a nutshell This study investigated if antibiotic treatment for endometritis affects the outcome of in vitro fertilization (IVF). They found that antibiotic treatment of CE improved IVF outcomes in patients who also experienced recurrent implantation failure. Some background Chronic endometritis (CE) is a condition caused by inflammation in the...
Read MoreIn a nutshell The aim of this phase 4 trial is to assess if a single dose of a gonadotrophin-releasing hormone (GnRH) agonist enhances implantation during in vitro fertilization (IVF). The main outcome to be measured is the rate of live births. This study is being conducted in New Jersey, in the United States. The details In very early pregnancy,...
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In a nutshell This study investigated whether endometriosis surgery impacted pregnancy rates as a result of in vitro fertilization (IVF). They found that the severe endometriosis resulted in lower IVF pregnancy rates and the optimal time for IVF is 7-25 months following endometriosis surgery. Some background Endometriosis is a chronic condition...
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In a nutshell This paper studied whether using testicular sperm is effective for men with severe oligospermia. Researchers reported a 50% pregnancy rate, all resulting in live births. Some background Oligospermia refers to a low sperm count in the ejaculate. It is a common cause of male infertility. Sperm in the ejaculate is often associated with...
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In a nutshell This study looked at in-vitro fertilization (IVF) outcomes in couples with unexplained infertility. Two egg fertilization techniques were compared: intracytoplasmatic sperm injection versus conventional insemination. Some background IVF involves the artificial joining of eggs and sperm in a laboratory dish. This is typically achieved...
Read MoreIn a nutshell This article outlines the current methods available to improve in vitro fertilization (IVF) success rates in women over 35 years old. The authors discuss the outcomes of a single embryo transfer of an embryo that has been genetically selected. Some background IVF involves the artificial matching of a...
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In a nutshell This study looked at the outcomes of a new egg retrieval strategy in women undergoing in-vitro fertilization (IVF). Researchers compared a 2-drug combination ("dual-trigger") to the standard hCG trigger injection. Some background IVF requires eggs retrieved from the ovaries to be fertilized by sperm in a laboratory dish. To...
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