In a nutshell The authors determined the effect of hormone therapy for the treatment of localized prostate cancer. Some background Localized prostate cancer is confined within the prostate gland. Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones active in prostate cancer,...
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In a nutshell The authors interpreted the results of a phase III trial on the use of enzalutamide (Xtandi) in treating patients with metastatic (cancer that has spread) hormone-resistant (castration-resistant) prostate cancer. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones...
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In a nutshell The authors determined the link between a specific hormone therapy and the risk of pneumonia in prostate cancer patients. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Gonadotropin-releasing...
Read MoreIn a nutshell This phase III trial aims to determine the effects of hypo-fractionated radiation compared to standard radiation therapy. The main outcome to be investigated is whether hypo-fractionated radiation has similar or better results when compared to standard radiation. This trial is recruiting in in Illinois, Oklahoma and Virginia, in the...
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In a nutshell The authors identified treatments available for men with advanced prostate cancer who were resistant to hormone therapy (castration-resistant). Some background Hormone therapy is a standard treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients...
Read MoreIn a nutshell The authors aimed to evaluate the effectiveness of lapatinib (Tyverb) as treatment for women with metastatic breast cancer (the tumor has spread to other organs) where previous treatment has proven ineffective. Some background Circulating tumor cells (CTC’s) are cells from a primary tumor that have migrated into the blood...
Read MoreIn a nutshell The authors aimed to determine the effects of taxanes when treating prostate cancer patients with hormone-resistant cancer. Some background Hormone therapy is a common prostate cancer treatment. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients may become hormone-resistant....
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In a nutshell The authors aimed to determine the effectiveness of exemestane (Aromasin) to treat premenopausal women with breast cancer and treatment outlook in comparison to tamoxifen (Nolvadex). Some background Tamoxifen is a type of hormone therapy used to treat breast cancer. This type of treatment is generally specific for hormone receptor...
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In a nutshell The authors aimed to determine if there was a link between patient age, tumor type and the spread of cancer. Some background Breast cancer metastasis is the spread of the cancer to other parts of the body; following original cancer of the breast. Age at original diagnosis and the area affected by the tumor are just two of the...
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In a nutshell The authors aimed to study the effects of a type of post-surgical radiation; radiation to only the affected area of the breast. Some background Radiation is a type of cancer treatment that is recommended following a lumpectomy (removal of the tumor and some surrounding tissue; breast remains intact). 'Brachytherapy' is...
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In a nutshell The authors aimed to determine the effect of orteronel in patients resistant to hormone treatment. Some background Hormone therapy is commonly used in prostate cancer treatment and involves targeting the male sex hormones active in prostate cancer, such as testosterone. In some cases patients receiving hormone therapy may become...
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In a nutshell The authors aimed to highlight treatments available for bone tumors resulting from prostate cancer. Some background When prostate cancer spreads outside of the prostate, tumors can form all over the body, particularly on the bone. Bone tumors can significantly affect patients by causing joint pain, nerve pain and fractures....
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