In a nutshell This study compared early metabolic changes across different types of androgen deprivation therapy (ADT). Authors reported that some metabolic changes were more pronounced with pharmacological ADT compared to surgical ADT. Some background ADT is a type of hormone therapy commonly used to treat advanced prostate cancer. ADT targets...
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In a nutshell The authors aimed to determine whether palbociclib (Ibrance) could help treat women hormone-receptor positive (HR+) and human epidermal growth factor 2 negative (HER2-) metastatic (cancer has spread) breast cancer. The addition of palbociclib showed consistent success against breast cancer that had become resistant...
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In a nutshell This study examined the effects of enzalutamide (Xtandi) in improving disease-related symptoms associated with advanced metastatic prostate cancer. The researchers concluded that enzalutamide treatment is effective in managing prostate cancer-derived bone tumors and pain among men with advanced prostate cancer. Some background When...
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In a nutshell This study examined the effects of enzalutamide (Xtandi) with respect to the site of metastatic castration-resistant prostate cancer. Researchers concluded that enzalutamide is a safe and effective treatment for all sites of metastases studied. Some background When prostate cancer spreads outside of the prostate (also called...
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In a nutshell The authors aimed to determine if palbociclib (Ibrance) could help treat women with metastatic (spread to other areas of the body) breast cancer. The researchers concluded that palbociclib showed good response rates from women with metastatic breast cancer whose cells expressed a protein called retinoblastoma (Rb). Some background...
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In a nutshell This study investigated the effects of health status in older patients with metastatic castration-resistant prostate cancer on treatment outcome with taxane-based chemotherapies. Researchers reported that taxane-based chemotherapies were associated with a significant survival benefit, regardless of age and health status. Some background...
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In a nutshell The authors aimed to determine the risk of Alzheimer's disease in patients who underwent hormone therapy for prostate cancer. Results concluded that there is an association between hormone therapy and Alzheimer's development, particularly in patients who underwent hormone therapy for more than 12 months. Some background...
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In a nutshell This study examined the effectiveness of palbociclib (Ibrance) in the treatment of hormone receptor-positive breast cancer patients. The authors found that palbociclib treatment increased progression free survival. Some background Major treatment options for hormone receptor-positive (HR+, dependent on the hormones estrogen and/or...
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In a nutshell The authors aimed to determine the risk of bone fractures in men who underwent hormone therapy. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. There are numerous types of hormone treatment. These include anti-androgen...
Read MoreIn a nutshell The authors determined the benefit of docetaxel (Taxotere) and prednisone (Deltasone) in treating metastatic (cancer that spreads) hormone-resistant prostate cancer. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. In...
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In a nutshell The authors determined the treatment options available for gynecomastia in prostate cancer patients. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Bicalutamide (Casodex, Cosudex, Calutide) is a common hormonal drug...
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In a nutshell The authors determined the benefit of combination treatment with gemcitabine (Gemzar) and oxaliplatin (Eloxatin) in hormone resistant (castration-resistant) prostate cancer. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone....
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