In a nutshell This phase 2 trial located in Maryland, United States, aims to determine whether a combination of gemcitabine (Gemzar) and docetaxel (Taxotere) is effective in patients with metastatic colorectal adenocarcinoma with CHFR and/or microsatellite instability. Patient's resposne to treatment will be measured. The details...
Read More
In a nutshell The authors evaluated whether there was a difference in the treatment response rates between invasive lobular carcinoma and invasive ductal carcinoma. Some background Invasive lobular carcinoma (ILC) is characterized as cancer that begins in the milk-producing lobules that then spreads to surrounding breast tissue. Invasive...
Read More
In a nutshell The authors determined the safety and effectiveness of abiraterone acetate (Zytiga) in patients with metastatic hormone-resistant prostate cancer. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients...
Read More
In a nutshell The authors compared the safety and effectiveness of pembrolizumab (Keytruda) to chemotherapy for the treatment of ipilimumab (Yervoy)-resistant melanoma. Some background Ipilimumab, an immunotherapy (treatment that uses the body’s own immune system to fight cancer), is an approved drug for the...
Read More
In a nutshell The authors reviewed the biology as well as current and future treatment options for eye melanoma. Some background Uveal melanoma is a rare cancer (melanoma) of the eye. It involves three parts of the eye (iris, ciliary body and choroid) known together as the uvea. Eye melanoma is associated with a high risk...
Read More
In a nutshell The authors analyzed the effectiveness and safety of retreatment with ipilimumab (Yervoy) in patients with advanced melanoma. Some background The survival rate in advanced melanoma is poor. Ipilimumab, an immunotherapy (treatment that uses the body’s own immune system to fight cancer), is an...
Read More
In a nutshell The authors aimed to evaluate a series of treatments used for advanced breast cancer; this was a review of chemotherapy drugs such as paclitaxel (Taxol), doxetaxel (Taxotere) and nab-paclitaxel (Abraxane). Some background Taxanes are a group of chemotherapy drugs used commonly in locally advanced (cancer has spread into nearby...
Read More
In a nutshell The authors aimed to determine the effectiveness of exemestane (Aromasin) to treat premenopausal women with breast cancer and treatment outlook in comparison to tamoxifen (Nolvadex). Some background Tamoxifen is a type of hormone therapy used to treat breast cancer. This type of treatment is generally specific for hormone receptor...
Read More
In a nutshell In this review, the authors aimed to assess the beneficial role of preventive radiation therapy to the head in small cell lung cancer (SCLC). Some background SCLC accounts for 13% of all lung cancers. It tends to grow and spread quickly to other parts of the body, often to the brain (brain metastasis). The available treatment...
Read More
In a nutshell This article evaluated the benefits of psychology treatments for breast cancer patients with depression. Some background Many women with breast cancer also suffer from depression (22%). This can lead to a decreased quality of life and overall prognosis (treatment outcome). 'Psychodynamic psychotherapy' is a form of...
Read More
In a nutshell The authors aimed to evaluate if the outcomes of surgery following chemotherapy are different based on the focality of breast cancer tumors. Some background Breast cancer can be characterised as 'unifocal', 'multifocal and 'multicentric'. This refers to the number of areas in which the cancer can be found...
Read More
In a nutshell The objective of this research was to analyze the safety and effectiveness of racotumomab (Vaxira) vaccine in advanced non-small cell lung cancer (NSCLC). Some background In the advanced stage (IIB/ IV) of NSCLC, cancer may spread throughout lungs, to adjacent lymph nodes (tiny, bean-shaped organs that help fight infections) and to...
Read More
