In a nutshell This study investigated the use of magnetic resonance (MR) imaging as a prognostic tool in primary breast cancer (BC) patients. The study concluded that MR imaging can identify features which can be used to help predict the risk of distant metastasis (cancer spread to other areas) in patients. Some background Between 20-30%...
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In a nutshell This study determined whether certain risk factors predicted outcomes in primary refractory Hodgkin lymphoma. The authors concluded that risk factors such as stage IV disease and cancer activity seen on imaging predicted worse overall outcomes. Some background Refractory disease Hodgkin lymphoma patients are those who are...
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In a nutshell This study compared the survival outcomes of two different age groups of relapsed and refractory Hodgkin lymphoma patients. The authors concluded that co-morbidities, not age, reduced survival rates after stem-cell surgery. Some background Hodgkin lymphoma (HL) is a type of cancer of the lymph system. It is generally highly...
Read MoreIn a nutshell This trial examined the quality-of-life (QOL) impact of an antibody therapy among patients who had already undergone standard treatment for relapsed- or refractory disease. The authors concluded that the treatment modestly decreased QOL during certain time periods only. Some background Hodgkin Lymphoma is generally highly...
Read MoreIn a nutshell This trial examined whether the immunotherapy atezolizumab (Tecentriq) is more effective than docetaxel (Taxotere) at treating non-small-cell lung cancer that has progressed passed first line treatment. The authors concluded that atezolizumab provided an overall survival benefit compared to docetaxel. Some background Docetaxel is the...
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In a nutshell This study examined the effects of a combination of two treatments, low-dose capecitabine (Xeloda) and docetaxel (Taxotere), versus docetaxel alone in patients with metastatic, HER2-negative breast cancer. The study concluded that combination treatment improved time to disease progression. Some background...
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In a nutshell This study assessed whether patients with relapsed- or refractory Hodgkin Lymphoma should be treated with radiation therapy. The authors concluded that radiation therapy was safe and prevented the return of the disease in certain patients. Some background Hodgkin lymphoma is a cancer of the lymph system. It is a...
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In a nutshell This trial examined the effectiveness of bendamustine in patients with Hodgkin lymphoma that did not respond to treatment or returned after a period without disease. The authors found that this treatment was effective in this population. Some background About 30% of Hodgkin lymphoma patients will either not respond to treatment...
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In a nutshell This trial examined the longer-term effectiveness of brentuximab vedotin (Adcetris) after stem cell transplant in patients with relapsed or refractory (did not respond to treatment) Hodgkin lymphoma. The authors concluded that patients who respond to brentuximab vedotin can achieve long-term disease control. Some background...
Read MoreIn a nutshell This article summarized some of the possible late effects of Hodgkin lymphoma treatment. Some background The standard treatment options for Hodgkin lymphoma are radiation and chemotherapy. These treatments have led to very high remission rates (no sign of disease) in many patients. Radiation and chemotherapy have also been associated...
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In a nutshell This study investigated the number of people affected by chemotherapy-induced peripheral neuropathy (CIPN). Risk factors for CIPN, and whether there was an increased risk of falls were also studied. The authors found that most long-term survivors of breast cancer had some CIPN symptoms. Obesity was the main risk factor. Patients...
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In a nutshell This study investigated the outcomes of rectal cancer patients with complete or near-complete response to chemotherapy and radiation therapy (CRT) who do not undergo surgery. Researchers reported that not undergoing surgery, in selected patients, is a safe option for treatment of rectal cancer. Some background The standard...
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