In a nutshell This study aimed to compare the outcomes of allogeneic stem cell transplant from sibling matched donors and unrelated donors in primary refractory acute myeloid leukemia patients. This study concluded that the donor type did not impact the outcomes for primary refractory acute myeloid leukemia patients. Some background...
Read MoreTreatment(s) already received-Bone marrow transplant Posts on Medivizor
Long-term outcomes for children who receive stem cell transplants for acute leukemia
In a nutshell This study aimed to identify ways to predict long-term outcomes of stem cell transplants for children with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). This study concluded that factors such as age, age and disease status at time of transplant and presence of chronic GVHD influenced the risk score for acute...
Read MoreCould interferon-alpha benefit acute leukemia patients who have minimal residual disease after stem cell transplants?
In a nutshell This study aimed to investigate the effectiveness of interferon-alpha (IFN-α) in acute leukemia patients with minimal residual disease after stem cell transplantation. This study concluded that IFN-α is an effective treatment for acute leukemia patients with minimal residual disease after stem cell...
Read MoreNovel treatments for patients with relapsed Hodgkin Lymphoma following autologous stem cell transplantation
In a nutshell This study examined the effect of new treatments for patients who have relapsed after an autologous stem cell transplantation. The authors concluded that patients treated with new therapies, including brentuximab vedotin (Adcetris), have significantly better outcomes. Some background Hodgkin lymphoma (HL) is generally...
Read MoreThe impact of co-morbidities on post-stem cell transplant survival in patients over 50
In a nutshell This study compared the survival outcomes of two different age groups of relapsed and refractory Hodgkin lymphoma patients. The authors concluded that co-morbidities, not age, reduced survival rates after stem-cell surgery. Some background Hodgkin lymphoma (HL) is a type of cancer of the lymph system. It is generally highly...
Read MoreThe effects of brentuximab vedotin on quality of life
In a nutshell This trial examined the quality-of-life (QOL) impact of an antibody therapy among patients who had already undergone standard treatment for relapsed- or refractory disease. The authors concluded that the treatment modestly decreased QOL during certain time periods only. Some background Hodgkin Lymphoma is generally highly...
Read MoreBendamustine is effective in Hodgkin lymphoma that has relapsed or did not respond to treatment
In a nutshell This trial examined the effectiveness of bendamustine in patients with Hodgkin lymphoma that did not respond to treatment or returned after a period without disease. The authors found that this treatment was effective in this population. Some background About 30% of Hodgkin lymphoma patients will either not respond to treatment...
Read More