In a nutshell This study aimed to analyze the impact of antithymocyte globulin doses in patients with acute myeloid leukemia in first complete remission undergoing transplantation. This study concluded that an antithymocyte globulin dose less than 6mg/kg is enough to prevent graft versus host disease. Doses higher than this impair disease control and...
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In a nutshell This study looked at the effect of surveillance scans after autologous stem cell transplantation (auto-SCT) in patients with relapsed or refractory diffuse large B-cell lymphoma. The study concluded that scanning everyone after auto-SCT has little benefit. Some background Diffuse large B-cell lymphoma (DLBCL) is the most common...
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In a nutshell This study aimed to investigate the combination of blinatumomab (Blincyto) and a tyrosine kinase inhibitor in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia. This study concluded that this combination was safe and effective for this group of patients. Some background Philadelphia...
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In a nutshell This study analyzed the results of 37 studies comparing myeloablative therapy and reduced intensity conditioning (RIC) before stem cell transplantation in patients with chronic lymphocytic leukemia (CLL). This study concluded that RIC was associated with lower mortality and better survival compared to myeloablative therapy. Some...
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In a nutshell This study examined the effect of donor type on allogeneic stem cell transplant outcomes in patients with relapsed Hodgkin lymphoma. This study reported reduced disease progression in patients with partially matched donors compared to identical matches. Some background While Hodgkin lymphoma is a curable disease, some patients...
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In a nutshell This study examined outcomes of autologous stem cell transplants after high-dose chemotherapy in non-Hodgkin lymphoma (NHL) patients with central nervous system (CNS) involvement. This study reported durable remission and good disease control for NHL with CNS involvement. Some background Many forms of NHL are treatable. When...
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Video information: In this informative and optimistic edition of “Ask the Expert,” Dr. Gareth Morgan, Professor of Medicine and Director of the UAMS Myeloma Institute, reveals what health prerequisites multiple myeloma patients must reach before they can become cured and what tools are available to help attain that goal. He also poses...
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In a nutshell This study aimed to investigate the thyroid function in acute myeloid leukemia (AML) patients who were treated with allogeneic hematopoietic stem cell transplant (allo-HSCT). This study concluded that a significant number of AML patients treated with allo-HSCT experience hyperthyroidism. Some background An allogeneic...
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Video information: On location at the recent 2017 American Society of Clinical Oncology meeting (ASCO), Dr. Hearn Jay Cho of Mount Sinai Hospital discusses news out of ASCO 2017 and what it means for myeloma patients and care partners. Dr. Cho highlights news out of the meeting, including how experts are manipulating the immune system, precision...
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In a nutshell This study aimed to investigate the post-hematopoietic (stem) cell transplant outcomes for older patients with AML in their second complete remission. This study concluded that hematopoietic cell transplant is a good treatment option, especially for patients with favorable- or intermediate-cytogenetic risk status. Some background...
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In a nutshell This article looks at the effect that autologous stem cell transplantation has on the fertility of women with Hodgkin or non-Hodgkin lymphoma. The study concluded that women had a surprisingly high rate of good fertility outcomes after autologous stem cell transplantation. Some background Autologous stem cell transplantation...
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In a nutshell This article looks at the effect that autologous stem cell transplantation has on the fertility of women with Hodgkin or non-Hodgkin lymphoma. The study concluded that women had a surprisingly high rate of good fertility outcomes after autologous stem cell transplantation. Some background Autologous stem cell transplantation...
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