In a nutshell This study investigated the occurrence and baseline risk factors of cancer occurrence in patients with rheumatoid arthritis (RA) treated with tofacitinib (Xeljanz) or tumor necrosis factor inhibitors (TNFis). The data showed a higher risk of cancer development with tofacitinib treatment compared to TNFis in these patients. Some...
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Can oral azacitidine maintenance promote longer survival in older patients with acute myeloid leukemia in first remission following chemotherapy?
In a nutshell This study evaluated the effectiveness of oral azacitidine (Onureg; Oral-AZA) maintenance treatment in older patients with acute myeloid leukemia (AML) in remission. The data showed that Oral-AZA maintenance therapy can be considered in older patients with AML for which hematopoietic stem cell transplantation (HSCT) is not an...
Read MoreEvaluating the effectiveness of magnetic stimulation in female urgency urinary incontinence
In a nutshell The study evaluated the effectiveness of magnetic stimulation (MS) in urgency urinary incontinence (UUI). The study found that MS showed promising results in treating UUI. Some background Urinary incontinence (UI) is the involuntary leakage of urine. Urinary incontinence is categorized into stress UI, urgency UI, and mixed UI. UUI is a...
Read MoreEvaluating the effectiveness and safety of TAC-302 in patients with detrusor underactivity and overactive bladder.
In a nutshell This study evaluated the effectiveness and safety of TAC-302 in patients with detrusor underactivity (DU) and overactive bladder (OAB). The study found that TAC-302 may benefit patients with DU. Some background Overactive bladder (OAB) occurs when the bladder muscle is too active. Instead of staying at rest as urine fills the bladder,...
Read MoreComparing the effectiveness of different intrauterine interventions for women with two or more implantation failures.
In a nutshell This study compared the effectiveness of different intrauterine interventions for women with two or more implantation failures. The data showed that platelet-rich plasma (PRP) was the most effective intrauterine intervention in improving pregnancy outcomes in these women. Some background In vitro fertilization (IVF) is a widely used...
Read MoreEvaluating the effectiveness and safety of taxanes combined with chemotherapy in patients with advanced triple negative breast cancer.
In a nutshell This study evaluated the effectiveness and safety of taxanes combined with chemotherapy in patients with advanced triple-negative breast cancer (TNBC). This study concluded that the combination of taxanes and chemotherapy is effective with manageable side effects in these patients. Some background TNBC is a subtype of BC that tests...
Read MoreComparing the effectiveness of high- and low-frequency pelvic floor muscle training on urinary incontinence episode frequency
In a nutshell The study compared the effectiveness of high- and low-frequency pelvic floor muscle training (PFMT) on urinary incontinence (UI) episode frequency in women with UI. The study found that high-frequency PFMT for 12 weeks was more effective than low-frequency PFMT in these patients. Some background Stress urinary incontinence (SUI) is an...
Read MoreEvaluating the effectiveness of letrozole/gonadotropin protocol in infertile women with PCOS
In a nutshell The study compared the effectiveness of letrozole (Femara)/gonadotropin combination to letrozole alone in infertile women with polycystic ovarian syndrome (PCOS). The study found that the combination of letrozole/gonadotropin was more effective than letrozole alone in these women. Some background Polycystic ovarian syndrome or...
Read MoreIs an alternative, chemotherapy-free approach possible for patients with acute promyelocytic leukemia?
In a nutshell This study compared the effectiveness of treatment with all-trans retinoic acid (ATRA; Retin-a) and arsenic trioxide (ATO; Trisenox) to ATRA-ATO with chemotherapy (CHT) in patients with newly diagnosed acute promyelocytic leukemia (APL). The data showed that treatment with ATRA-ATO was equally effective as ATRA-ATO plus CHT in these...
Read MoreEvaluating the outcomes of GreenLight laser photoselective vaporization in patients with large prostates for the treatment of benign prostatic hyperplasia.
In a nutshell This study evaluated the outcomes of GreenLight laser photoselective vaporization (PVP) in patients with large prostates for the treatment of benign prostatic hyperplasia (BPH). The data showed that GreenLight PVP was safe and effective in these patients. Some background Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement...
Read MoreEvaluating the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis in patients with a good Endometriosis Fertility Index score.
In a nutshell This study evaluated the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis (EM) in patients with a good Endometriosis Fertility Index (EFI) score. The data showed that both IVF and non-IVF treatments showed similar clinical pregnancy and live birth rates in these...
Read MoreEvaluating the effectiveness and safety of toripalimab in combination with chemotherapy as a first-line treatment for advanced NSCLC.
In a nutshell This study investigated the effectiveness and safety outcomes of toripalimab (Tuoyi) in combination with chemotherapy as a first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that toripalimab in combination with chemotherapy significantly improved overall survival and survival without cancer...
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