In a nutshell This study evaluated the effectiveness and safety of TAC-302 in patients with detrusor underactivity (DU) and overactive bladder (OAB). The study found that TAC-302 may benefit patients with DU. Some background Overactive bladder (OAB) occurs when the bladder muscle is too active. Instead of staying at rest as urine fills the bladder,...
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In a nutshell This study compared the effectiveness of different intrauterine interventions for women with two or more implantation failures. The data showed that platelet-rich plasma (PRP) was the most effective intrauterine intervention in improving pregnancy outcomes in these women. Some background In vitro fertilization (IVF) is a widely used...
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In a nutshell This study evaluated the effectiveness and safety of taxanes combined with chemotherapy in patients with advanced triple-negative breast cancer (TNBC). This study concluded that the combination of taxanes and chemotherapy is effective with manageable side effects in these patients. Some background TNBC is a subtype of BC that tests...
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In a nutshell The study compared the effectiveness of high- and low-frequency pelvic floor muscle training (PFMT) on urinary incontinence (UI) episode frequency in women with UI. The study found that high-frequency PFMT for 12 weeks was more effective than low-frequency PFMT in these patients. Some background Stress urinary incontinence (SUI) is an...
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In a nutshell The study compared the effectiveness of letrozole (Femara)/gonadotropin combination to letrozole alone in infertile women with polycystic ovarian syndrome (PCOS). The study found that the combination of letrozole/gonadotropin was more effective than letrozole alone in these women. Some background Polycystic ovarian syndrome or...
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In a nutshell This study compared the effectiveness of treatment with all-trans retinoic acid (ATRA; Retin-a) and arsenic trioxide (ATO; Trisenox) to ATRA-ATO with chemotherapy (CHT) in patients with newly diagnosed acute promyelocytic leukemia (APL). The data showed that treatment with ATRA-ATO was equally effective as ATRA-ATO plus CHT in these...
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In a nutshell This study evaluated the outcomes of GreenLight laser photoselective vaporization (PVP) in patients with large prostates for the treatment of benign prostatic hyperplasia (BPH). The data showed that GreenLight PVP was safe and effective in these patients. Some background Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement...
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In a nutshell This study evaluated the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis (EM) in patients with a good Endometriosis Fertility Index (EFI) score. The data showed that both IVF and non-IVF treatments showed similar clinical pregnancy and live birth rates in these...
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In a nutshell This study investigated the effectiveness and safety outcomes of toripalimab (Tuoyi) in combination with chemotherapy as a first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that toripalimab in combination with chemotherapy significantly improved overall survival and survival without cancer...
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In a nutshell The study evaluated the effectiveness and safety of radium-223 dichloride (Xofigo) treatment in real-world patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that radium-223 dichloride treatment was well tolerated and reduced pain in real-world patients with mCRPC spread to the bone. Some...
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In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
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In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
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