In a nutshell This study compared the real-world outcomes of two widely used drugs, abiraterone (Zytiga) and enzalutamide (Xtandi) in patients diagnosed with metastatic castrate-resistant prostate cancer (mCRPC). The study showed that both drugs were effective in these patients in a real-world setting, with better results...
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In a nutshell This study evaluated the outcomes of autologous stem cell transplantation (ASCT) for patients with recurrent multiple myeloma (MM). This study found that long-term outcomes for these patients were promising, especially for patients who had the transplant right away after a first relapse. Some background Multiple myeloma (MM) is a type of...
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In a nutshell This study looked at vagus nerve stimulation (VNS) as a treatment for arm weakness after stroke. It found that VNS combined with standard rehabilitation improved arm function significantly more than standard rehab alone. Some background After a stroke, some nerves do not work as they should. This means that the muscles...
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In a nutshell This study looked at the use of renal denervation in patients with true resistant hypertension. It found that this procedure reduced blood pressure compared to medicine alone. Some background High blood pressure (BP) which is not controlled on three blood pressure-lowering medications including a diuretic (water pill) is...
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In a nutshell This study compared acupuncture with anti-depressant medications for the treatment of depression in patients who have had a stroke. It found that post-stroke depression was less severe 3-8 weeks after acupuncture compared to anti-depressant medication. Some background Depression affects approximately 1 in 3 patients...
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In a nutshell This review aimed to compare the benefits and risks associated with targeted therapy (TT) and chemoimmunotherapy (CIT) as frontline treatments for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Some background The number of treatment options for CLL and SLL has increased in the last few years....
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In a nutshell This review aimed to compare the benefits and risks associated with targeted therapy (TT) and chemoimmunotherapy (CIT) as frontline treatments for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Some background The number of treatment options for CLL and SLL has increased in the last few years....
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In a nutshell This review aimed to compare the benefits and risks associated with targeted therapy (TT) and chemoimmunotherapy (CIT) as frontline treatments for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Some background The number of treatment options for CLL and SLL has increased in the last few years. For a long...
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In a nutshell This review aimed to compare the benefits and risks associated with targeted therapy (TT) and chemoimmunotherapy (CIT) as frontline treatments for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Some background The number of treatment options for CLL and SLL has increased in the last few years. For a long...
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In a nutshell This study compared the effectiveness of transcutaneous electrical nerve stimulation (TENS) combined with solifenacin succinate (SS; Vesicare) to SS alone, in patients with overactive bladder (OAB). The data showed that TENS in combination with SS was more effective than SS on its own in these patients. Some...
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In a nutshell This study evaluated the impact of idelalisib (Zydelig) interruption or dose reductions on clinical outcomes in patients with relapsed/refractory (r/r) indolent (painless) non-Hodgkin lymphoma (iNHL) and chronic lymphocytic leukemia (CLL). This study showed that stopping idelalisib and reducing the dose due to side effects was...
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In a nutshell This study evaluated the impact of idelalisib (Zydelig) interruption or dose reductions on clinical outcomes in patients with relapsed/refractory (r/r) indolent (painless) non-Hodgkin lymphoma (iNHL) and chronic lymphocytic leukemia (CLL). This study showed that stopping idelalisib and reducing the dose due to side effects was associated...
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