In a nutshell This study looked at the use of robotic-assisted CyberKnife radiosurgery to treat iris melanomas. It found that this is a promising treatment for iris melanoma. Some background Melanomas are the most common tumors of the eye. Eye melanomas usually occur at the back of the eye, but sometimes they affect the iris (the colored...
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In a nutshell This study looked at the use of vibegron (Gemtesa) for overactive bladder (OAB) in older patients. It found that vibegron was equally effective in younger and older patients and did not have significant impact on heart disease in older patients. Some background OAB is a condition that affects mainly older...
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In a nutshell This study compared the long-term outcomes of umbilical cord (UC) blood transplantation versus unrelated donor transplantation (UD) in patients with acute myeloid leukemia (AML). The data showed that long-term outcomes for patients in complete remission two years after transplantation was not impacted by donor...
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In a nutshell This study compared the outcomes of proteasome inhibitors (PIs) versus immunomodulators (IMs) as maintenance therapy for patients with newly diagnosed MM. The data showed that PIs maintenance increased the survival outcomes compared to IMs in these patients. Some background Multiple myeloma (MM) is a type of cancer that comes from blood...
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In a nutshell This study investigated the frequency and outcomes of contralateral axillary metastasis (CAM) in patients with inflammatory breast cancer (IBC). The data showed that CAM was common at diagnosis in patients with IBC and was best identified by ultrasound and positron emission tomography (PET). Some background IBC is a rare and aggressive...
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In a nutshell This study compared the effectiveness and safety outcomes of atezolizumab (Tecentriq) alone or with chemotherapy (CT) for the treatment of patients with advanced non-small-cell lung cancer (NSCLC). The data showed that atezolizumab alone might be a better treatment option than atezolizumab plus CT for these patients. Some...
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In a nutshell This article compared the safety and effectiveness of PD-L1/PD-1 immunotherapies (IT) for non-small cell lung cancer (NSCLC). The authors found that in the first-line setting, the most effective treatments for PD-L1 positive NSCLC were atezolizumab (Tecentriq), pembrolizumab (Keytruda)/chemotherapy (CT) combination, and nivolumab...
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In a nutshell This article looked at the impact of nerve-sparing (NS) surgery on positive surgical margin (PSM) location and the recurrence of tumors in patients following radical prostatectomy (RP; prostate removal surgery). The authors found that having NS surgery on both sides of the prostate increased the risk of PSM and was associated with a higher...
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In a nutshell This study evaluated the rates of local, regional, and distant recurrence between patients who received immediate or delayed autologous deep inferior epigastric perforators (DIEP) flap breast reconstruction (BR). The data showed that there is an increased risk for breast cancer (BC) recurrence in women who received a delayed BR...
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In a nutshell This study investigated the safety and effectiveness of afatinib (Gilotrif) in patients with non-small cell lung cancer (NSCLC) who have not previously received EGFR tyrosine kinase inhibitors (TKIs). Data showed that afatinib was well tolerated and improved the outcomes of these patients. Some background NSCLC...
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In a nutshell This study examined the use of paclitaxel (Taxol) and carboplatin (Paraplatin) as weekly chemotherapy (CT) with trastuzumab (Herceptin) and pertuzumab (Perjeta) in HER2+ breast cancer (BC) in order to reduce toxicity rates. The authors found that the weekly regimen of chemotherapy can be considered an alternative to standard chemotherapy...
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In a nutshell This trial looked at the long-term effectiveness and safety of ixazomib (Ixa; Ninlaro) in combination with lenalidomide (R; Revlimid), and dexamethasone (d; Decadron) for the treatment of relapsed/refractory (RR) multiple myeloma (MM). The authors found that there was an improved survival with Ixa-Rd...
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