In a nutshell This study looked at the use of transurethral microwave thermotherapy (TUMT) for the treatment of benign prostatic hyperplasia (BPH) compared to transurethral resection of the prostate (TURP). It found that both treatments are similarly effective in managing BPH symptoms. TUMT has fewer side effects than TURP, but it also...
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Evaluating short-course radiation therapy followed by chemotherapy for patients with rectal cancer.
In a nutshell This study evaluated short-course radiation therapy (RT) followed by chemotherapy as a non-surgical treatment of patients with rectal cancer (RC). The data showed that treatment with short-course RT and chemotherapy is safe and effective for these patients. Some background Colorectal cancer (CRC) is one of the most common types of...
Read MoreApalutamide plus androgen deprivation therapy preserves health-related quality of life in patients with non-metastatic castration-resistant prostate cancer.
In a nutshell This study reported the long-term effects on the health-related quality of life (HR-QoL) of apalutamide (Erleada) in combination with androgen deprivation therapy (ADT) in patients with non-metastatic castration-resistant prostate cancer (nmCRPC). The data showed that apalutamide plus ADT preserved HR-QoL in these patients. Some background...
Read MoreDoes tyrosine kinase inhibitors therapy after surgery benefit patients with EGFR-mutant resected NSCLC?
In a nutshell This study evaluated whether patients with non-small-cell lung cancer (NSCLC) having genetic mutations could benefit from epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) therapy after surgery. The data showed that EGFR-TKI therapy after surgery significantly improved survival without disease progression in...
Read MoreIs osimertinib an effective treatment for EGFR-mutant advanced non-small cell lung cancer in a real-world practice?
In a nutshell This study looked at the use of osimertinib (Tagrisso) for the treatment of EGFR-mutant advanced non-small-cell lung cancer (NSCLC) in a real-world practice. It found that osimertinib was confirmed to improve survival without cancer progressing, while the occurrence of blood clots was more common in a real-world...
Read MoreIs peficitinib an effective treatment for rheumatoid arthritis?
In a nutshell This study looked at the use of peficitinib (Smyraf) for the treatment of rheumatoid arthritis (RA) from the perspective of patients and their doctors. It found that peficitinib improved symptoms of RA and led to increased ability to work and carry out daily activities compared to placebo. Some background RA is a chronic...
Read MoreWhich treatment is best for stress incontinence, surgery or bulking agents?
In a nutshell This study compared the use of bulking agents versus surgery for the treatment of stress urinary incontinence (SUI). It found that bulking agents were less effective for SUI compared to surgical treatment. Some background Stress urinary incontinence (SUI) is a condition that is common in women. It leads to leaking of urine...
Read MoreEvaluating the occurrence and predictors of peripheral nerve disease after breast cancer treatment.
In a nutshell This study evaluated the occurrence and clinical predictors of peripheral neuropathy (PN; nerve damage) in long-term survivors of breast cancer (BC). The data showed that PN is an important long-term consequence of taxane-based chemotherapy in survivors of BC. Some background BC is one of the most common forms of cancer in women....
Read MoreEvaluating the effectiveness and safety of anlotinib combined with radiotherapy to the head for patients with brain metastases from NSCLC.
In a nutshell This study evaluated the effectiveness and safety of combining cranial radiotherapy (CRT; radiotherapy tot the head) with and without anlotinib (AL3818) for the treatment of patients with non-small cell lung cancer (NSCLC) and brain metastases (BM). The data showed that anlotinib plus CRT significantly improved survival without brain...
Read MoreWhich surgical procedure for BPH is associated with persistent medication use?
In a nutshell This study determined the percentage of men with benign prostatic hyperplasia (BPH) that still needed BPH medication after surgical therapy for lower urinary tract symptoms (LUTS). The authors concluded that laser enucleation of the prostate (LEP) had the lowest percentage of patients that still needed BPH medication. Some...
Read MoreDoes a disposable home electrical stimulation device improve symptoms of urinary incontinence in women?
In a nutshell This study looked at the use of the Pelviva electro-stimulation device for the treatment of urinary incontinence (UI) in women. It found that the Pelviva device improves UI compared to standard treatment. Some background Urinary incontinence (UI) is a very common problem for women, especially in older age. It involves...
Read MoreWhat is the initial management of benign prostatic hyperplasia?
In a nutshell This study reviewed the initial management of benign prostatic hyperplasia (BPH). Some background BPH is a condition in which the prostate grows and can compress the urethra (the tube that passes urine out of the bladder), leading to difficulty passing urine. Symptoms include needing to urinate frequently,...
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