In a nutshell This study aimed to investigate the impact of salvage treatment using either chemotherapy (CT) or allogeneic hematopoietic stem cell transplant (allo-HSCT) on the overall outcome in patients with refractory (unresponsive) acute myeloid leukemia (AML). This study concluded that allo-HSCT benefits these patients and that direct...
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In a nutshell This study assessed the effectiveness and safety of eplerenone (Inspra) treatment for diabetic nephropathy (DN; diabetic kidney disease) in patients with type 2 diabetes (T2D). The data showed that eplerenone can be an effective supplement to existing clinical treatment in patients with DN. Some background DN is kidney damage...
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In a nutshell This study compared the effectiveness and safety of teneligliptin (Tenelia) to placebo in patients with type 2 diabetes (T2D) that was inadequately controlled with triple oral antidiabetic drugs (OADs). The study showed that teneligliptin may be considered as a fourth add-on OAD treatment in these patients. Some background T2D is...
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In a nutshell This study evaluated the effectiveness of daratumumab (Darzalex)-containing regimens in patients with multiple myeloma (MM) unresponsive to lenalidomide (Revlimid) maintenance therapy. The data showed that daratumumab-containing therapies are effective regimens in these patients. Some background Multiple myeloma (MM) is a type...
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In a nutshell This study evaluated the effectiveness of adding dutasteride (Avodart) to tadalafil (Cialis) for the treatment of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). The data showed that adding dutasteride to tadalafil is a good treatment option for improving LUTS in these patients. Some background...
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In a nutshell This study evaluated the effectiveness and safety of opicapone (Ongentys) for the treatment of non-motor symptoms in patients with Parkinson's disease (PD). The data showed that opicapone improved the non-motor symptoms and quality of life (QoL) with manageable side effects in patients with PD. Some background Parkinson's disease...
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In a nutshell This study investigated the effectiveness and safety of sugemalimab (Cejemly) after treatment with concurrent or sequential chemoradiotherapy (CRT) in patients with unresectable stage III non-small cell lung cancer (NSCLC). The data showed that sugemalimab significantly increased the survival without cancer worsening with manageable...
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In a nutshell This study investigated the effect of total neoadjuvant therapy (TNT) versus standard neoadjuvant chemoradiotherapy (CRT) and planned adjuvant chemotherapy on the survival of patients with locally advanced rectal cancer (LARC). The data showed that TNT did not increase survival compared with standard CRT and planned adjuvant...
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In a nutshell This study assessed the effectiveness and safety of combined therapy of tamsulosin (Flomax) and two different traditional herbal medicines in patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). The study showed that tamsulosin with Ryutanshakanto provided pain relief in patients with chronic...
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In a nutshell This study evaluated the effects of different antioxidants on sperm quality and the pregnancy rate of male infertility without a clear cause. The data showed that L-Carnitine had the highest probability of being the most effective antioxidant to increase sperm motility (movement) and sperm shape. ω-3 fatty acid had the highest...
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In a nutshell This study evaluated the benefits of adding androgen deprivation therapy (ADT) to radiation therapy (RT) and the benefit of extending the duration of ADT in men with localized prostate cancer (PCa). The data showed that the addition of ADT to RT and extending the duration of ADT administered after RT significantly improved the survival...
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In a nutshell This study compared the effectiveness and safety of immunotherapy versus standard treatment options in patients with metastatic colorectal cancer (mCRC). The data showed that immunotherapy tended to improve the survival outcomes in these patients. Some background Colorectal cancer (CRC) is one of the most common types of cancer...
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