In a nutshell This study evaluated the effectiveness and safety of zanubrutinib (Brukinsa) versus ibrutinib (Imbruvica) in patients with Waldenström Macroglobulinemia (WM). The data showed that zanubrutinib had higher long-term response rates and lower side effects than ibrutinib in these patients. Some background WM is a type of cancer in which...
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In a nutshell This study evaluated the effectiveness of lenalidomide (Revlimid)-containing regimens in patients with first relapsed multiple myeloma (MM). The data showed that daratumumab (Darzalex) combined with lenalidomide and dexamethasone (Rd) regimen significantly increased the survival without cancer worsening with fewer serious side effects...
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In a nutshell This study evaluated the effectiveness of acupuncture for the treatment of anxiety in patients with Parkinson’s disease (PD). The data showed that acupuncture was an effective treatment for anxiety and improved the well-being of these patients. Some background Parkinson's disease (PD) is a disorder in which part of the brain is...
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In a nutshell This study investigated the effectiveness and safety of gilteritinib (Xospata) plus azacitidine (Vidaza) versus azacitidine alone for patients with newly diagnosed FMS-like tyrosine kinase 3 (FLT3)-mutated acute myeloid leukemia (AML) who are unfit for intensive chemotherapy. The data showed that gilteritinib plus azacitidine...
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In a nutshell This study evaluated the effectiveness and safety of robotic versus laparoscopic abdominoperineal resections (APRs) for the treatment of patients with low rectal cancer (RC). The data showed that robotic APRs significantly reduced surgical trauma and promoted recovery after surgery compared with laparoscopic APRs in these patients. Some...
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In a nutshell This study compared the effectiveness and safety between immune checkpoint inhibitors (ICIs) and docetaxel (Taxotere) therapy alone in patients with non-small cell lung cancer (NSCLC). The data showed ICIs significantly improved the survival outcomes with fewer serious side effects compared to docetaxel alone for the treatment of patients...
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In a nutshell This study compared the effectiveness and safety of intralesional verapamil (Calan; ILV) and collagenase Clostridium histolyticum (Xiaflex; CCH) injections in men with Peyronie’s disease (PD). The data showed that CCH therapy was more effective than ILV, with a higher high level of patient satisfaction rate in the short term...
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In a nutshell This study evaluated the effectiveness and safety of noninvasive cerebellar stimulation (NICS) in improving the balance and walking function of patients with stroke. The data showed that NICS improved the balance and walking function in these patients. Some background A stroke is caused by a reduction in blood flow to the...
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In a nutshell This analysis investigated the relationship between anti-diabetic medications and the risk of fractures in patients with type 2 diabetes (T2D). The data showed that glucagon-like peptide-1 receptor agonists (GLP1-RAs) and sulfonylurea (SU) provided better protection against fractures compared to thiazolidinedione (TZD) or dipeptidyl...
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In a nutshell This study reviewed the effect of high-dose vitamin D2 (ergocalciferol) supplementation on delaying the onset of type 1 diabetes (T1D) in children and adolescents with newly diagnosed T1D. The authors recommended maintaining a safe and effective high-dose vitamin D2 concentration of 30-60 ng/mL for delaying the onset of T1D in...
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In a nutshell The study evaluated the effectiveness of injections of autologous endometrial cells (AEC) and platelet-rich plasma (PRP) in infertile women with a thin endometrium (uterine lining). The study found that PRP injections and injections of AEC suspended in PRP improved the cells and thickness of the endometrium. Some...
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In a nutshell The study evaluated the effectiveness of aquatic therapeutic exercise in breast cancer survivors for improving symptoms and quality of life. The study found that aquatic therapeutic exercise effectively improved fatigue, pain, and quality of life in these patients. Some background Breast cancer (BC) is the most common...
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