In a nutshell This study investigated the effectiveness of bevacizumab plus chemotherapy and deep electro-hyperthermia (DEH) for advanced colon cancer (CC). Researchers suggested that this treatment improves the outcomes of these patients. Some background Colorectal cancer is a common cancer worldwide. Around 50-60% of these patients...
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Stereotactic body radiotherapy improves treatment response in metastatic colorectal cancer
In a nutshell This study investigated the effectiveness of stereotactic body radiotherapy (SBRT) in metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that SBRT is associated with improved tumor response and manageable side effects. Some background Colorectal cancer is the second most commonly diagnosed cancer in...
Read MoreStereotactic body radiotherapy improves survival of patients with metastatic colorectal cancer
In a nutshell This study investigated the effectiveness of stereotactic body radiotherapy (SBRT) in metastatic (spread to other parts of the body) colorectal cancer outcomes. Researchers suggested that SBRT improves survival in these patients. Some background Colorectal cancer is the third most common cancer worldwide. The liver is the most...
Read MoreRadiotherapy improves cancer outcomes in patients with advanced colorectal cancer
In a nutshell This study investigated the effectiveness and safety of radiotherapy in patients with metastatic (spread to other parts of the body) colorectal cancer (mCRC). Researchers suggested that radiotherapy could be a safe option for the treatment of these patients. Some background Colorectal cancer is the third most frequently diagnosed cancer....
Read MoreLocal treatment in metastatic colorectal cancer is a safe option for the elderly and for patients with other medical conditions
In a nutshell This study investigated whether local ablative methods (LAT; non-invasive procedures) of treatment can be used in patients with colorectal cancer that are older or have other medical conditions. Researchers suggested that these procedures may be performed safely in these patients. Some background Age is a major risk factor for colorectal...
Read MoreLooking for colorectal patients with liver and lung metastasis to undergo surgery and chemotherapy
In a nutshell This phase 2 trial recruiting in Houston, Texas (US) aims to compare the effect of having a liver tumor surgically removed along with chemotherapy to chemotherapy alone in patients whose colorectal cancer has spread to their liver and lungs. The main outcome to be measured is overall survival (time from treatment until death from any...
Read MoreTreatment for lung metastases: how good is radiofrequency ablation for colorectal cancer patients?
In a nutshell This study investigated the effectiveness of radiofrequency ablation (RFA) for patients with colorectal lung metastases (cancer that has spread from the colon or rectum to the lung). Some background Colorectal cancer is one of the most common cancers worldwide. For up to 25% of patients the colon or rectal cancer will have spread to...
Read MoreLung invasion: what are the outcomes of colorectal cancer patients who have undergone lung surgery?
In a nutshell This study examined cancer relapse rates and treatment options for patients with colorectal lung metastases (colorectal cancer that has spread to the lungs) after curative lung surgery. Some background Roughly 20% of patients with colorectal cancer will have cancer in a distant organ by the time they are diagnosed. The cancer will...
Read MoreWhat are the long-term outcomes of patients with cancer in the rectum and in a limited number of other organs?
In a nutshell This study examined the outcome of patients with rectal cancer that had spread to a limited number of other organs after treatment of the rectal tumor. Some background Rectal cancer can spread from the rectum to other organs and tissues of the body. This is referred to as metastasis. If the cancer only spreads to a small...
Read MoreDabrafenib increases progression-free survival in patients with metastatic melanoma with BRAF mutations
In a nutshell This phase 3 clinical trial compared the safety and efficacy of dabrafenib to a standard treatment for melanoma, dacarbazine in patients with metastatic melanoma. Some background BRAF is a protein that helps cells grow and multiply. A genetic defect can cause the BRAF protein to malfunction (BRAF mutation). A BRAF mutation is...
Read MoreRadiofrequency ablation as a treatment for pulmonary metastases after surgical treatment for liver metastases from colorectal cancer
In a nutshell This study looked at the use of radiofrequency ablation (RFA) as a treatment for colorectal cancer which has spread to the lungs (pulmonary metastasis). Overall, the results showed that RFA treatment gives patients a better survival rate than the previous method of systemic chemotherapy which used to be the best treatment option for...
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