In a nutshell This study investigated whether cancer that has spread to the peritoneal surface (the lining of the abdominal cavity) can be treated as effectively as cancer that has spread to the liver in colorectal cancer patients. Some background The liver is the most common metastatic site (site for the cancer to...
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In a nutshell This study investigated whether certain patients should not be considered for combined liver and colon surgery. Some background For patients with colorectal cancer surgery remains the only option for cure. In up to 25% of patients with colorectal cancer the cancer will already have spread (metastasized) to the liver at diagnosis. For...
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In a nutshell This paper studied the safety and effectiveness of yttrium-90 radioembolization (use of radiation to cut off blood flow) in breast cancer that has spread to the liver. Some background In breast cancer liver metastases, cancer spreads from the breast to the liver. Breast cancer liver metastases are associated with...
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In a nutshell The authors provided information on 4 different types of treatment for patients with colorectal cancer and liver metastases. Some background The liver is the most common site of metastasis (cancer spread) and disease recurrence (return) in colorectal cancer. Only 20-25% of patients with colorectal cancer liver metastases...
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In a nutshell This study examined if genetic analysis can predict when FOLFOX or FOLFIRI chemotherapy would be more useful. Some background The treatment of choice for colon cancer is surgical resection (removal of part of the intestine). However, if the cancer has spread (metastasized), chemotherapy is often the only option. Two drug...
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In a nutshell This study examined the effect of hepatic-artery infusion combined with systemic chemotherapy on patients with inoperable colorectal liver metastases. Some background Any cancer involving the colon or rectum is called colorectal cancer. Frequently, this cancer spreads to the liver (colorectal liver metastasis), and often in...
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In a nutshell This meta-analysis (an analysis of data combined from several similar studies) compared the efficacy of radiofrequency ablation versus liver resection in patients with colorectal cancer liver metastases. Some background Colorectal cancer liver metastasis refers to cancer that has spread to the liver. Liver...
Read MoreIn a nutshell This study examined the safety and efficacy of a two-step hepatectomy combined with hepatic artery infusion chemotherapy as treatment for liver-spread colorectal cancer. Some background A common location for metastasis (spread) of colorectal cancer is the liver. Surgical removal of the liver tumor (hepatectomy) can increase survival...
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In a nutshell This study assessed the survival rates and characteristics of metastatic colorectal cancer (CRC) patients with liver-limited disease (LLD) who underwent conversion chemotherapy. Some background Colorectal cancer patients may develop metastases (spread of the cancer to other distant organs and tissues of the body) and the liver is one...
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In a nutshell This study investigated if the amount of blood lost during surgery to remove metastatic tumors (cancer spread to distant organs of the body) on the liver from primary colorectal cancer (CRC) could be used as an indicator of long term survival and tumor recurrence (return of the cancer). Some background The liver is a common site for...
Read MoreIn a nutshell This study investigated the combination of hepatic artery infusion (HAI) and systemic chemotherapy for the treatment of unresectable colorectal cancer liver metastasis (CRLM). Some background The liver is the most common site of metastasis (cancer spread) in colorectal cancer patients. Surgical treatments that remove all liver tumors...
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In a nutshell This article compares the use of radiofrequency ablation (RFA) and a robotic method of treatment using directed radiation to liver metastases from colorectal cancer which have been deemed not suitable for surgical treatment. The study shows robotic radiation treatment is safe and comparable to RFA, with a trend towards being better...
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