In a nutshell This study investigated the effectiveness of stereotactic body radiotherapy (SBRT) in metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that SBRT is associated with improved tumor response and manageable side effects. Some background Colorectal cancer is the second most commonly diagnosed cancer in...
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In a nutshell This trial is examining the effectiveness of mFOLFOX6 (oxaliplatin, leucovorin, fluorouracil) and nivolumab (Opdivo) with and without a new cancer vaccine (CV301) for patients with colorectal cancer that has spread to the liver. The main outcome will be overall survival. This trial is being conducted in California and New Jersey,...
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In a nutshell This study investigated the effectiveness of stereotactic body radiotherapy (SBRT) in metastatic (spread to other parts of the body) colorectal cancer outcomes. Researchers suggested that SBRT improves survival in these patients. Some background Colorectal cancer is the third most common cancer worldwide. The liver is the most...
Read MoreIn a nutshell This study investigated whether local ablative methods (LAT; non-invasive procedures) of treatment can be used in patients with colorectal cancer that are older or have other medical conditions. Researchers suggested that these procedures may be performed safely in these patients. Some background Age is a major risk factor for colorectal...
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In a nutshell This study investigated the impact of laparoscopic (LPS) compared with open surgery on colorectal liver metastasis (when cancer spreads to the liver). Researchers suggested that LPS is a safe option to treat liver metastasis in colorectal cancer patients. Some background The liver is the most common site of colorectal cancer...
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In a nutshell This phase 2 trial recruiting in Houston, Texas (US) aims to compare the effect of having a liver tumor surgically removed along with chemotherapy to chemotherapy alone in patients whose colorectal cancer has spread to their liver and lungs. The main outcome to be measured is overall survival (time from treatment until death from any...
Read MoreIn a nutshell This study investigated the surgical treatment and associated outcomes of colorectal liver metastasis (the cancer has spread to the liver). Researchers suggested that individualized care for each patient is crucial to better plan the treatment and extent survival. Some background The liver is the most common place for colorectal...
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In a nutshell This study investigated the benefits of chemotherapy in colorectal cancer patients with inoperable liver metastasis (the cancer has spread to the liver). Researchers reported that chemotherapy increases survival in colorectal patients with inoperable liver metastasis. Some background Only 10-20% of colorectal patients with...
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In a nutshell This study investigated which types of immune cells are more active in fighting colorectal cancer which has spread to the liver. It was found that T cells are the most active. Some background It is thought that the immune system response to colorectal cancer (CRC) is an important factor in determining whether the disease progresses...
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In a nutshell The authors aimed to assess the effectiveness of traditional Chinese medicine used with conventional breast cancer treatments on breast cancer survival. Some background Traditional Chinese medicine is an alternative therapy that can complement breast cancer treatments. This generally includes various forms of herbal medicine,...
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In a nutshell The authors assessed the safety and efficacy of two treatment combinations for colorectal cancer patients who have liver invasion but who are not eligible for surgery. Some background For patients with colorectal cancer the cancer is most likely to invade the liver if it spreads. Surgery is the best treatment option if the cancer has...
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In a nutshell This study is being carried out in New York and New Jersey. It will examine whether adding panitumumab (Vectibix) to chemotherapy reduces the risk of the cancer returning in colorectal cancer patients with liver metastases (cancer that has spread to the liver). The authors will also record any adverse events experienced and patient...
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