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Evaluating treatment outcomes of fractionated stereotactic radiotherapy in patients with small and moderate-sized brain metastases.

Evaluating treatment outcomes of fractionated stereotactic radiotherapy in patients with small and moderate-sized brain metastases.

Posted by on Sep 17, 2022 in Melanoma | 0 comments

In a nutshell This study investigated the effectiveness and safety of fractionated stereotactic radiation therapy (FSRT) for patients with small and moderate-sized brain metastases (BM). The data showed that FSRT was safe and effective in patients with BM of any size with excellent local control. Some background Stereotactic radiosurgery (SRS) is...

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Evaluating treatment outcomes of fractionated stereotactic radiotherapy in patients with small and moderate-sized brain metastases.

Evaluating treatment outcomes of fractionated stereotactic radiotherapy in patients with small and moderate-sized brain metastases.

Posted by on Sep 17, 2022 in Lung cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of fractionated stereotactic radiation therapy (FSRT) for patients with small and moderate-sized brain metastases (BM). The data showed that FSRT was safe and effective in patients with BM of any size with excellent local control. Some background Stereotactic radiosurgery (SRS) is...

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Which sequence of treatment should be given first – local or systemic treatment for patients with non-small cell lung cancer and brain metastases?

Which sequence of treatment should be given first – local or systemic treatment for patients with non-small cell lung cancer and brain metastases?

Posted by on Feb 13, 2022 in Lung cancer | 0 comments

In a nutshell This study evaluated which sequence of treatment should be given first, local or systemic (whole-body) treatment for patients with non-small cell lung cancer (NSCLC) and brain metastases (BMs). The data showed that systemic treatment followed by local treatment was associated with longer survival for patients with NSCLC and BM. Some...

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Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

Posted by on Oct 31, 2021 in Melanoma | 0 comments

In a nutshell This study investigated the optimal doses of hypofractionated stereotactic radiation therapy (HSRT) for patients with brain metastases (BM). The data showed that a HSRT dose of 30 Gy or higher delivered in 5 daily fractions was safe and effective in these patients. Some background Stereotactic radiosurgery (SRS) is commonly...

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Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

Posted by on Oct 31, 2021 in Lung cancer | 0 comments

In a nutshell This study investigated the optimal doses of hypofractionated stereotactic radiation therapy (HSRT) for patients with brain metastases (BM). The data showed that a HSRT dose of 30 Gy or higher delivered in 5 daily fractions was safe and effective in these patients. Some background Stereotactic radiosurgery (SRS) is commonly used in...

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Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

Evaluating treatment outcomes of hypofractionated stereotactic radiotherapy in patients with brain metastases.

Posted by on Oct 31, 2021 in Breast cancer | 0 comments

In a nutshell This study investigated the optimal doses of hypofractionated stereotactic radiation therapy (HSRT) for patients with brain metastases (BM). The data showed that a HSRT dose of 30 Gy or higher delivered in 5 daily fractions was safe and effective in these patients. Some background Stereotactic radiosurgery (SRS) is commonly used in...

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Evaluating the impact of brain metastasis in the effectiveness of immunotherapy in patients with non-small cell lung cancer

Evaluating the impact of brain metastasis in the effectiveness of immunotherapy in patients with non-small cell lung cancer

Posted by on Sep 5, 2021 in Lung cancer | 0 comments

In a nutshell This study evaluated the effectiveness of immune checkpoint inhibitors (ICI) versus chemotherapy in patients with non-small cell lung cancer (NSCLC) andy brain metastases (BM). The data showed that the effectiveness of ICIs was similar in patients with no BM symptoms and/or treated BMs. For patients with BMs, ICI combination therapy was...

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Is selpercatinib effective in treating brain metastases in RET fusion-positive non-small cell lung cancer?

Is selpercatinib effective in treating brain metastases in RET fusion-positive non-small cell lung cancer?

Posted by on Jul 31, 2021 in Lung cancer | 0 comments

In a nutshell This study looked at the effectiveness selpercatinib (Retevmo) for the treatment of patients with RET fusion-positive non-small cell lung cancer (NSCLC) that has spread to the brain. The authors found that selpercatinib was effective in these patients.  Some background RET mutations are genetic abnormalities that can cause some...

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Controlling brain metastasis with localized radiotherapy.

Controlling brain metastasis with localized radiotherapy.

Posted by on Feb 17, 2021 in Melanoma | 0 comments

In a nutshell This study evaluated the impact of radiotherapy (RT) on controlling brain metastasis (BM). The study suggested that a single dose of RT was effective in controlling small BM. Larger BM could be controlled more effectively with multiple rounds of RT. Some background The spread of cancer from the original tumor to other parts of the...

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Is radiosurgery in combination with other cancer therapies safe in patients with brain metastasis?

Is radiosurgery in combination with other cancer therapies safe in patients with brain metastasis?

Posted by on Jan 31, 2021 in Lung cancer | 0 comments

In a nutshell The aim of this study was to evaluate the safety of giving stereotactic radiosurgery (SRS) at the same time as other cancer treatments for patients who have brain metastasis. The study found that SRS given in combination with chemotherapy, immunotherapy, or targeted therapy was safe with low levels of side effects. Some background The...

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Does immune checkpoint therapy and radiotherapy combination improve response in treating brain metastasis from non-small cell lung cancer and melanoma?

Does immune checkpoint therapy and radiotherapy combination improve response in treating brain metastasis from non-small cell lung cancer and melanoma?

Posted by on Dec 30, 2020 in Melanoma | 0 comments

In a nutshell The study evaluated the timing of radiotherapy (RT) and immune-checkpoint therapy (ICT) on the outcomes of patients with brain metastasis (BrM) resulting from melanoma and non-small cell lung cancer (NSCLC). The authors found that RT and ICT given at the same time may improve response and delay recurrence in these patients. Some...

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