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Site(s) of metastases-Bone(s) Posts on Medivizor

Evaluating the safety of re-treatment with radium-223

Posted by on Sep 16, 2019 in Prostate cancer | 0 comments

In a nutshell This study aimed to evaluate the safety and effectiveness of radium-223 (Xofigo, formerly known as Alpharadin) in patients with advanced prostate cancer that has spread to the bones and who have had this treatment previously. This study found that re-treatment with radium-223 was well tolerated and with good results. Some background...

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How effective is radiotherapy for the treatment of advanced prostate cancer?

Posted by on Apr 13, 2019 in Prostate cancer | 0 comments

In a nutshell This study investigated the effectiveness of prostate radiotherapy (RT) in prostate cancer (PC). They found that prostate RT may improve survival in men with PC and fewer than 5 bone metastasis (cancer that has spread to the bones).  Some background Prostate cancer (PC) is a common and treatable cancer in men. One common type...

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Looking for men with prostate cancer to test chemotherapy in combination with radiotherapy

Posted by on Feb 23, 2019 in Prostate cancer | 0 comments

In a nutshell This trial evaluates the effectiveness of using chemotherapy in combination with radium-223 (a type of internal radiotherapy). The main outcome to be measured is overall survival. This trial is taking place in the United States. The details Prostate cancer is an uncontrolled growth of the cells which make up the prostate gland. Prostate...

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Abiraterone plus prednisone therapy in men with advanced prostate cancer

Posted by on Aug 12, 2017 in Prostate cancer | 0 comments

In a nutshell The authors aimed to determine the benefit of abiraterone acetate (Zytiga) plus prednisone (Deltasone) with hormone therapy in men with newly diagnosed, advanced prostate cancer. The authors concluded that adding abiraterone acetate plus prednisone to hormone therapy significantly increased overall survival and progression-free survival...

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Cancer spread to the spine: Predictors of survival

Posted by on Sep 12, 2016 in Prostate cancer | 0 comments

In a nutshell This study examined predictors of survival for cancer patients with spinal bone metastases. Authors reported that stable and unstable spinal bone metastases had similar survival rates. However, factors predictive of survival were different between groups. Some background When cancer spreads outside of the prostate (known as...

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Hormone and targeted therapy in the treatment of bone tumors in metastatic prostate cancer

Posted by on Jul 9, 2015 in Prostate cancer | 0 comments

In a nutshell The authors analyzed the effect of using hormone therapy and targeted therapy, in combination, to treat bone tumors in prostate cancer patients. Some background Hormone therapy is a common treatment for prostate cancer. It reduces the level of male sex hormones (e.g. testosterone) in the body or prevent them from affecting...

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Denosumab; reduces skeletal complications in metastatic castration-resistant prostate cancer

Posted by on Dec 31, 2014 in Prostate cancer | 0 comments

In a nutshell The authors evaluated skeletal events to determine whether denosumab (Prolia) reduced the risk of skeletal complications in metastatic castration-resistant prostate cancer.  Some background Denosumab is a drug used to treat metastatic castration-resistant prostate cancer (cancer which has spread from the prostate and...

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A new radiotherapy drug for patients with prostate cancer that has spread to the bone

Posted by on Aug 1, 2013 in Prostate cancer | 0 comments

In a nutshell This phase 3 clinical trial assessed the efficacy and safety of radium-223 dichloride or radium-223 (Xofigo) in patients with prostate cancer that has spread to the bone.  Some background Testosterone, the main male sex hormone, promotes the growth of prostate cancer. A treatment option for prostate cancer patients is castration...

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