In a nutshell This study compared the effectiveness of treatment with all-trans retinoic acid (ATRA; Retin-a) and arsenic trioxide (ATO; Trisenox) to ATRA-ATO with chemotherapy (CHT) in patients with newly diagnosed acute promyelocytic leukemia (APL). The data showed that treatment with ATRA-ATO was equally effective as ATRA-ATO plus CHT in these...
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Evaluating the outcomes of GreenLight laser photoselective vaporization in patients with large prostates for the treatment of benign prostatic hyperplasia.
In a nutshell This study evaluated the outcomes of GreenLight laser photoselective vaporization (PVP) in patients with large prostates for the treatment of benign prostatic hyperplasia (BPH). The data showed that GreenLight PVP was safe and effective in these patients. Some background Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement...
Read MoreEvaluating the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis in patients with a good Endometriosis Fertility Index score.
In a nutshell This study evaluated the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis (EM) in patients with a good Endometriosis Fertility Index (EFI) score. The data showed that both IVF and non-IVF treatments showed similar clinical pregnancy and live birth rates in these...
Read MoreEvaluating the effectiveness and safety of toripalimab in combination with chemotherapy as a first-line treatment for advanced NSCLC.
In a nutshell This study investigated the effectiveness and safety outcomes of toripalimab (Tuoyi) in combination with chemotherapy as a first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that toripalimab in combination with chemotherapy significantly improved overall survival and survival without cancer...
Read MoreEvaluating the risk factors for ischemic or hemorrhagic stroke recurrence
In a nutshell This study investigated the risk factors for ischemic or hemorrhagic stroke recurrence and the impact of antiplatelet therapy in patients with intracranial hemorrhage (ICH; brain bleed). The data showed that the risk of stroke recurrence is high in these patients. Hypertension (high blood pressure) is a risk factor for ischemic and...
Read MoreEvaluating the effectiveness and safety of radium-223 dichloride treatment in real-world patients with metastatic castration-resistant prostate cancer.
In a nutshell The study evaluated the effectiveness and safety of radium-223 dichloride (Xofigo) treatment in real-world patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that radium-223 dichloride treatment was well tolerated and reduced pain in real-world patients with mCRPC spread to the bone. Some...
Read MoreEvaluating the risk of cardiovascular side effects in cancer patients treated with PD-1/PD-L1 inhibitors.
In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
Read MoreEvaluating the risk of cardiovascular side effects in cancer patients treated with PD-1/PD-L1 inhibitors.
In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
Read MoreEvaluating the risk of cardiovascular side effects in cancer patients treated with PD-1/PD-L1 inhibitors.
In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
Read MoreEvaluating the effects of split-belt treadmill versus tied-belt treadmill training on gait adaptation in patients with Parkinson’s disease.
In a nutshell This study evaluated the effects of split-belt treadmill (SBT) versus tied-belt treadmill (TBT) training on gait adaptation in patients with Parkinson’s disease (PD). The data showed that SBT training significantly improved gait adaptation compared to TBT in these patients. Some background PD is a disorder in which part of...
Read MoreEvaluating the effectiveness and safety of adding isatuximab to lenalidomide, bortezomib, and dexamethasone combination for patients with newly diagnosed transplantation-eligible multiple myeloma.
In a nutshell This study evaluated the effectiveness and safety of adding isatuximab (Sarclisa) to lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (Decadron) combination as induction therapy for patients with newly diagnosed transplantation-eligible multiple myeloma (MM). The data showed that the addition of isatuximab to lenalidomide,...
Read MoreEvaluating the effectiveness and safety of a tumor bed boost after whole breast irradiation following breast-conserving surgery in patients with non-low-risk ductal carcinoma in situ.
In a nutshell This study investigated the effectiveness and safety of a tumor bed (where the tumor was present) boost after whole breast irradiation (WBI) following breast-conserving surgery (BCS) in patients with non-low-risk ductal carcinoma in situ (DCIS). The data showed that a tumor bed boost after WBI following BCS reduced local recurrence (return...
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