In a nutshell This study investigated the occurrence and baseline risk factors of cancer occurrence in patients with rheumatoid arthritis (RA) treated with tofacitinib (Xeljanz) or tumor necrosis factor inhibitors (TNFis). The data showed a higher risk of cancer development with tofacitinib treatment compared to TNFis in these patients. Some...
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Can oral azacitidine maintenance promote longer survival in older patients with acute myeloid leukemia in first remission following chemotherapy?
In a nutshell This study evaluated the effectiveness of oral azacitidine (Onureg; Oral-AZA) maintenance treatment in older patients with acute myeloid leukemia (AML) in remission. The data showed that Oral-AZA maintenance therapy can be considered in older patients with AML for which hematopoietic stem cell transplantation (HSCT) is not an...
Read MoreCan cardiovascular risk factors be reduced by consumption of soymilk and probiotics in patients with type 2 diabetes?
In a nutshell This study examined the effects of consuming soymilk and probiotics on risk factors related to heart and blood vessel diseases in patients with type 2 diabetes (T2D). The study showed that the consumption of soymilk with probiotics might improve cardiovascular (CV) risk factors in these patients. Some background T2D is a...
Read MoreEvaluating the effectiveness of magnetic stimulation in female urgency urinary incontinence
In a nutshell The study evaluated the effectiveness of magnetic stimulation (MS) in urgency urinary incontinence (UUI). The study found that MS showed promising results in treating UUI. Some background Urinary incontinence (UI) is the involuntary leakage of urine. Urinary incontinence is categorized into stress UI, urgency UI, and mixed UI. UUI is a...
Read MoreEvaluating the effectiveness and safety of TAC-302 in patients with detrusor underactivity and overactive bladder.
In a nutshell This study evaluated the effectiveness and safety of TAC-302 in patients with detrusor underactivity (DU) and overactive bladder (OAB). The study found that TAC-302 may benefit patients with DU. Some background Overactive bladder (OAB) occurs when the bladder muscle is too active. Instead of staying at rest as urine fills the bladder,...
Read MoreComparing the effectiveness of different intrauterine interventions for women with two or more implantation failures.
In a nutshell This study compared the effectiveness of different intrauterine interventions for women with two or more implantation failures. The data showed that platelet-rich plasma (PRP) was the most effective intrauterine intervention in improving pregnancy outcomes in these women. Some background In vitro fertilization (IVF) is a widely used...
Read MoreEvaluating the effectiveness and safety of taxanes combined with chemotherapy in patients with advanced triple negative breast cancer.
In a nutshell This study evaluated the effectiveness and safety of taxanes combined with chemotherapy in patients with advanced triple-negative breast cancer (TNBC). This study concluded that the combination of taxanes and chemotherapy is effective with manageable side effects in these patients. Some background TNBC is a subtype of BC that tests...
Read MoreComparing the effectiveness of high- and low-frequency pelvic floor muscle training on urinary incontinence episode frequency
In a nutshell The study compared the effectiveness of high- and low-frequency pelvic floor muscle training (PFMT) on urinary incontinence (UI) episode frequency in women with UI. The study found that high-frequency PFMT for 12 weeks was more effective than low-frequency PFMT in these patients. Some background Stress urinary incontinence (SUI) is an...
Read MoreEvaluating the effectiveness of letrozole/gonadotropin protocol in infertile women with PCOS
In a nutshell The study compared the effectiveness of letrozole (Femara)/gonadotropin combination to letrozole alone in infertile women with polycystic ovarian syndrome (PCOS). The study found that the combination of letrozole/gonadotropin was more effective than letrozole alone in these women. Some background Polycystic ovarian syndrome or...
Read MoreEvaluating the effectiveness of physical exercise programs in breast cancer survivors on health-related quality of life, physical fitness, and body composition
In a nutshell The study evaluated the effectiveness of physical exercise (PE) programs in breast cancer (BC) survivors on health-related quality of life (HRQoL), physical fitness, and body composition. The study concluded that PE programs do have a positive impact on BC survivors’ HRQoL, physical fitness, and body composition. Some background...
Read MoreHow beneficial is a Mediterranean diet and physical activity to females with rheumatoid arthritis?
In a nutshell This study investigated the effect of a Mediterranean diet (MD) intervention with physical activity on rheumatoid arthritis (RA) disease status and the risk of cardiovascular diseases in women. The data showed that a personalized MD plan along with physical activity (PA) may provide benefits to females with RA. Some background RA is a...
Read MoreHow does physical activity affect the occurrence of major diabetes-related complications?
In a nutshell This study evaluated evidence on the association between physical activity and major diabetes-related complications in patients with diabetes. The authors concluded that physical activity was associated with a reduction in the occurrence of major diabetes-related complications, even if performed at levels lower than recommended. Some...
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