In a nutshell This study compared the Mediterranean diet (MD) with the low-fat diet (LFD) in patients with coronary artery disease (CAD). It found that after 3 months the MD was associated with higher omega-3 levels than the LFD. Some background Cholesterol is the name commonly used for the fats in the blood. Cholesterol can block the...
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In a nutshell This study looked at the 30-year risk of heart disease in patients with Hodgkin lymphoma (HL) treated with radiotherapy. It found that radiotherapy led to a small increase in the risk of death from heart disease or stroke in these patients. Some background HL is often treated with a combination of chemotherapy and...
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In a nutshell This study looked at the effect of safinamide (Xadago) on rapid eye movement (REM) sleep behavioral disorder (RBD) in patients with Parkinson's disease (PD). It found that safinamide 50 mg daily improved RBD symptoms in these patients. Some background Patients with PD sometimes suffer from REM sleep...
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In a nutshell This study looked at the use of closed-loop glucose control treatment for patients with type 2 diabetes (T2D) requiring dialysis. It found that compared to standard insulin therapy, closed-loop glucose control led to improved glucose control in these patients. Some background Closed-loop glucose control is a form of insulin...
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In a nutshell This study evaluated the effectiveness and safety of triple combination therapy with immune and targeted therapies in patients with stage III-IV melanoma. The data showed that triple combination therapy was associated with increased survival benefits with manageable side effects for these patients. Some background Melanoma is an...
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In a nutshell This study evaluated the effectiveness of immune checkpoint inhibitors (ICI) versus chemotherapy in patients with non-small cell lung cancer (NSCLC) andy brain metastases (BM). The data showed that the effectiveness of ICIs was similar in patients with no BM symptoms and/or treated BMs. For patients with BMs, ICI combination therapy was...
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In a nutshell This study evaluated the benefits of denosumab (Xgeva) on the bone health of women with early-stage breast cancer (BC). The data showed that denosumab improved bone-related outcomes in women with high-risk early-stage BC Some background BC is one of the most common forms of cancer in women. Early-stage BC is used to describe BC that is...
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In a nutshell This study looked at the impact of carotenoids to protect against the development of diabetic retinopathy (DR; eye disease). It found that daily carotenoid supplementation may improve the health of the retina and improve subtle changes in vision caused by DR. Some background DR is one of the most serious complications...
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In a nutshell The study evaluated the association of interleukin-2 (IL2) receptor (R) levels in the blood (a protein present on immune cells) in selecting a treatment for advanced-stage follicular lymphoma with a low tumor burden (FL-LTB). The study showed that patients with high IL-2R levels had better survival when treated with...
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In a nutshell This study aimed to investigate the link between various treatments for castration-resistant prostate cancer (CRPC) and cognitive (mental) dysfunction in older men. The main finding was that the treatments assessed did not appear to have an impact on cognitive function. Some background CRPC is prostate cancer that keeps growing...
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In a nutshell This study compared acalabrutinib (Calquence) and ibrutinib (Imbruvica) for the treatment of patients with chronic lymphocytic leukemia (CLL). The data showed that both drugs had similar effectiveness while acalabrutinib showed fewer cardiovascular side effects compared to ibrutinib. Some background Chronic lymphocytic...
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In a nutshell This study assessed the safety and impact on the growth of nilotinib (Tasigna) in children with chronic myeloid leukemia (CML). The data indicated reduced growth rates with nilotinib treatment in children with CML. Some background Chronic myeloid leukemia (CML) is rare in children. However, it affects younger patients more...
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