In a nutshell This study determined the percentage of men with benign prostatic hyperplasia (BPH) that still needed BPH medication after surgical therapy for lower urinary tract symptoms (LUTS). The authors concluded that laser enucleation of the prostate (LEP) had the lowest percentage of patients that still needed BPH medication. Some...
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In a nutshell This study examined the association between long-term use of three different tyrosine kinase inhibitors (TKIs) and the occurrence of vascular (blood vessel) adverse events (side effects; VAEs) in patients with chronic myeloid leukemia (CML). The data showed a possibly higher risk of developing VAEs when patients with CML were...
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In a nutshell This study explored the risk factors for fragility fractures in patients with rheumatoid arthritis (RA). The authors concluded that aging, disease-related factors, and previous fracture history are important risk factors for fragility fractures in these patients. Some background RA is a chronic, systemic inflammatory disease that affects...
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In a nutshell This study looked at the use of the Pelviva electro-stimulation device for the treatment of urinary incontinence (UI) in women. It found that the Pelviva device improves UI compared to standard treatment. Some background Urinary incontinence (UI) is a very common problem for women, especially in older age. It involves...
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In a nutshell This study reviewed the initial management of benign prostatic hyperplasia (BPH). Some background BPH is a condition in which the prostate grows and can compress the urethra (the tube that passes urine out of the bladder), leading to difficulty passing urine. Symptoms include needing to urinate frequently,...
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In a nutshell This study compared progesterone injected under the skin to vaginal progesterone after an embryo transfer. It found that under-the-skin progesterone was just as effective as vaginal progesterone, and led to similar pregnancy rates. Some background In vitro fertilization (IVF) is a common infertility treatment that involves transferring...
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In a nutshell This study aimed to compare enasidenib (Idhifa) to current standard of care therapies for patients with relapsed/refractory (r/r) acute myeloid leukemia (AML) and an isocitrate dehydrogenase 2 (IDH2) mutation who are ineligible for hematopoietic stem cell transplantation (HSCT). This study concluded that enasidenib significantly...
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In a nutshell This study evaluated the effect of brain metastases (BMs) status on immunotherapy effectiveness in patients with advanced lung cancer (LC). The data showed that the effectiveness of immunotherapy was similar in patients with or without BMs. Some background In 20-40% of patients with advanced LC, cancer spreads from the lung to the brain...
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In a nutshell This study compared the outcomes between radical prostatectomy (RP; prostate-removal surgery) and different types of radiotherapy (RT) in older patients with localized prostate cancer (PCa). The study found that RT offers similar cancer-specific outcomes to RP for low- to intermediate-risk patients. Some background...
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In a nutshell This study compared the effectiveness and safety of S-1 (tegafur/gimeracil/oteracil) and oxaliplatin (Eloxatin) combined with bevacizumab (Avastin) or with cetuximab (Erbitux) in patients with previously untreated advanced colorectal cancer with wild-type KRAS. This study concluded that the safety and effectiveness of...
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In a nutshell This study looked at the use of sacral neuromodulation (SNM) with the InterStim device in patients with overactive bladder (OAB). It found that SNM improved the symptoms of OAB over 3 years. Some background OAB is a condition in which the bladder contracts involuntarily leading to a sudden, urgent need to urinate....
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In a nutshell This study looked at the use of electrical stimulation (ES) for the treatment of stress urinary incontinence (SUI) in women. It found that ES improved incontinence-related quality of life over in the short-term. Some background SUI is a condition in which urine leaks out involuntarily when increased pressure is...
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