In a nutshell This study examined if the outcomes of stem cell transplants (SCT) have improved for young patients with relapsed or refractory Hodgkin lymphoma (HL) over time. The results showed that SCT has improved the survival rate and reduced the relapse rate of HL in young patients in recent years. Some background While initial treatment is...
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Long-term effects of ofatumumab and chlorambucil in previously untreated patients with chronic lymphocytic leukemia
In a nutshell The study evaluated the long-term effectiveness and safety of Ofatumumab (Arzerra) and chlorambucil (Leukeran) (CHL) in patients with previously untreated chronic lymphocytic leukemia (CLL). The authors found that the combination therapy safely improved clinical outcomes in such patients in 5 years, compared to chlorambucil alone. Some...
Read MoreEvaluating the safety of dapagliflozin in patients with type 2 diabetes
In a nutshell This study looked at the side effects of dapagliflozin (Farxiga) for patients with type 2 diabetes (T2D). It found that dapagliflozin was well tolerated and led to less kidney injury for patients with T2D. Some background T2D is a disorder that causes high levels of glucose (sugar) in the blood. Over time, high blood glucose can cause a...
Read MoreThe impact of statin use in patients with multiple myeloma
In a nutshell The investigators looked at the effects of cholesterol-lowering drugs from the statin group in patients with multiple myeloma (MM). The study found improved survival in patients who used statins before and after the diagnosis was made. Some background Multiple myeloma (MM) is a cancer resulting in abnormal proliferation of...
Read MoreHemopoietic stem cell transplant after chimeric antigen receptor T-cell therapy in patients with relapsed/refractory B-cell acute lymphoblastic leukemia
In a nutshell This study aimed to investigate if a hemopoietic stem cell transplant should be carried out after chimeric antigen receptor T cell therapy in patients with B-cell acute lymphoblastic leukemia. This study concluded that this treatment path led to high event-free survival in these patients. Some background...
Read MoreHow common are side effects of the heart in patients with non-Hodgkin lymphoma who receive CHOP or R-CHOP chemotherapy?
In a nutshell This study examined how common side effects of the heart, including heart failure, were among patients with non-Hodgkin lymphoma who received CHOP or R-CHOP chemotherapy. The results showed that only a minority developed side effects and that older patients and female patients were more likely to develop them. Some background Both...
Read MoreHow effective is BV-DHAP chemotherapy to treat patients with relapsed or refractory Hodgkin lymphoma?
In a nutshell This study examined the effectiveness and safety of the chemotherapy combination BV-DHAP for patients with relapsed or refractory Hodgkin lymphoma (HL). The authors found that BV-DHAP was an effective and safe treatment to progress patients to high-dose chemotherapy and stem cell transplant. Some background During treatment, some...
Read MoreDo stem cell transplants improve patients’ long-term survival?
In a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
Read MoreDo stem cell transplants improve patients’ long-term survival?
In a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
Read MoreDo stem cell transplants improve patients’ long-term survival?
In a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
Read MoreDo stem cell transplants improve patients’ long-term survival?
In a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
Read MoreDo stem cell transplants improve patients’ long-term survival?
In a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
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