In a nutshell This study investigated the effectiveness and safety of regorafenib (Stivarga) treatment in older patients with colorectal cancer (CRC). Researchers suggested that this treatment has similar effects in younger and older patients. Some background CRC is the third most common cancer worldwide. More than half are diagnosed in patients older...
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In a nutshell This study examined the safety and effectiveness of targeted therapy abemaciclib (Verzenio) for patients with relapsed or refractory mantle cell lymphoma (MCL). The results showed that abemaciclib had promising effectiveness and was relatively safe in these patients. Some background MCL is an aggressive type of lymphoma. During...
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In a nutshell This study examined if brachytherapy, a type of radiotherapy, is more effective with or without hormonal therapy for patients with localized prostate cancer. The authors found that patients survived longer without cancer worsening after treatment with brachytherapy and hormonal therapy. Some background Brachytherapy (BT) is a type...
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In a nutshell This study examined if acupuncture is an effective treatment for patients with nerve damage caused by chemotherapy for breast cancer. The results showed that patients had improved sensory and muscle symptoms, less pain, and improved quality of life following acupuncture treatment. Some background One side effect of chemotherapy is...
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In a nutshell This study aimed to investigate second treatments in patients with chronic myeloid leukemia (CML) who had been initially treated with second-generation tyrosine kinase inhibitors (TKI). This study concluded that switching from second-generation TKIs in these patients was relatively uncommon. Some background...
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In a nutshell This study investigated the effectiveness of repetitive transcranial magnetic stimulation (RTMS) in treating mental and physical symptoms of patients with Parkinson's disease (PD). Researchers suggested that RTMS improves the treatment outcomes of these patients. Some background PD affects 1% of the population over the age of 60...
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In a nutshell This study investigated treatment for nocturia in women. They found that desmopressin (Noctiva) and antimuscarinic (AM) drugs are effective. Some background Nocturia is a condition where there is an increased need to urinate at night. Nocturnal incontinence (NI) is the term used to describe bedwetting. Nocturia...
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In a nutshell This review looked at whether SGLT2 inhibitors increase the risk of ketoacidosis in patients with type 2 diabetes (T2D). It found that long-term use of these medications increases the risk of ketoacidosis, particularly for older patients. Some background Type 2 diabetes (T2D) is a disorder involving high levels of glucose (sugar) in...
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In a nutshell This study aimed to investigate post-transplant cyclophosphamide treatment in patients with acute myeloid leukemia. This study concluded that this treatment is safe and effective in these patients. Some background Post-transplant cyclophosphamide (PTCy) is an immune system suppressant. It can be used after...
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In a nutshell The report recommends several treatment modifications for patients with leukemia during the high-risk period of the COVID-19 pandemic. The main recommendations are to reduce clinic visits, use less intensive chemotherapy, and care through telemedicine for effective treatment. Some background Managing patients with leukemia during...
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In a nutshell This study investigated if cardiovascular function (CVF) is altered by in vitro fertilization (IVF). They found that IVF may cause short-term changes to CVF in women. Some background In vitro fertilization (IVF) is used to treat infertility. The first step of IVF involves harvesting eggs. Women inject hormones to stimulate the...
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In a nutshell This study investigated if blood pressure drugs that target the angiotensin-converting enzyme (ACE) affect COVID-19 outcomes. They found that ACE drugs were not associated with worse outcomes in COVID-19. Some background Hypertension or high blood pressure (BP) is a common condition. Anti-hypertensive (AHT) drugs are one of...
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