In a nutshell This study looked at the quality of life for patients with advanced follicular lymphoma (FL) who were treated with obinutuzumab (Gazyva) and chemotherapy compared to those treated with rituximab (Rituxan) and chemotherapy. It found that both targeted antibody therapies improved quality of life for patients with advanced FL. Some background...
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How effective are therapies to prevent bone loss in patients with breast cancer?
In a nutshell This study examined the effectiveness of three commonly used therapies to prevent bone loss in patients with hormone-positive breast cancer (BC). The results showed that the therapies prevented bone loss and fractures but to different degrees. Some background Many patients with BC are classified as hormone-positive. This means...
Read MoreCan bowel side effects caused by radiotherapy be reduced by a spacer tool in patients with prostate cancer?
In a nutshell This study examined if a hydrogel spacer tool improved long-term quality of life for patients with prostate cancer (PC) who received radiotherapy (RT). The results showed that the spacer significantly reduced bowel side effects and improved patients’ quality of life. Some background RT is an effective therapy for patients with...
Read MoreDo sperm parameters influence intrauterine insemination outcomes?
In a nutshell This study compared sperm concentration and quality with intrauterine insemination (IUI) outcomes. It found that IUI outcomes were similar for couples with high and low sperm quality. Some background IUI is an infertility procedure in which sperm are injected directly into the uterus. IUI is often combined with ovarian...
Read MoreDoes ICSI timing affect pregnancy outcomes?
In a nutshell This study looked at routine variations in timing during intracytoplasmic sperm injection (ICSI). It found that changes in timing may affect egg quality, but did not alter pregnancy outcomes. Some background ICSI is an infertility treatment in which a single sperm cell is injected into the oocyte (egg). ICSI is most commonly used for...
Read MoreCan home urine LH testing improve egg retrieval?
In a nutshell This study looked at using home urine tests of luteinizing hormone (LH) prior to egg collection. It found that home LH tests were a convenient, cost-saving, and effective method to confirm the final egg maturation prior to collection. Some background Egg collection is an infertility procedure which is used prior to egg donation or in...
Read MoreHigher or lower radiotherapy dose for patients with non-Hodgkin lymphoma undergoing stem cell transplantation?
In a nutshell This study examined how effective and safe a higher radiotherapy dose was for patients with non-Hodgkin lymphoma (NHL) undergoing stem cell transplantation (SCT). The authors found that patients who received a lower radiotherapy dose survived longer and had fewer side effects than the higher dose. Some background NHL is a cancer of...
Read MoreHow should patients with diabetes manage their health during the COVID-19 pandemic?
In a nutshell This article made recommendations for patients with diabetes on how to manage their health during the COVID-19 pandemic. Some background Coronavirus disease 2019 (COVID-19) is an infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This causes a chest infection that can potentially be fatal. Some...
Read MoreWhat are the effects of sacral neuromodulation therapy in patients with non-responsive overactive bladder following onabotulinumtoxinA therapy?
In a nutshell This paper reviewed the outcomes of patients with non-responsive overactive bladder (OAB) who were treated with sacral neuromodulation (SNM) after onabotulinumtoxinA (BTX, Botox) therapy. The main finding was SNM may be successful for treating non-responsive OAB. Some background OAB is characterized by having a strong urge to...
Read MoreCancer-related cognitive impairment in chronic lymphocytic leukemia
In a nutshell This study aimed to investigate cancer-related cognitive (thinking and reasoning) impairment in patients with chronic lymphocytic leukemia. This study concluded that disease biology may contribute to cancer-related cognitive impairment, independent of treatment. Some background Cancer-related cognitive impairment...
Read MoreReviewing optimal treatment options for chronic lymphocytic leukemia
In a nutshell This study aimed to investigate treatment options for chronic lymphocytic leukemia (CLL). This study concluded that treatment results from clinical trials may not be seen in a real-life setting and that novel agents can improve outcomes for these patients. Some background Traditional treatments for CLL include...
Read MoreCan iGlarLixi improve blood glucose control in patients receiving basal insulin?
In a nutshell This study looked at whether iGlarLixi (Soliqua), a combination of long-acting insulin glargine (Lantus) and lixisenatide (Lyxumia), can improve glucose control for patients with type 2 diabetes (T2D) uncontrolled with long-acting insulin alone. It found that iGlarLixi improved overall and after-meal blood sugar control compared to insulin...
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