In a nutshell This study looked at whether adding antioxidants to the media used to culture oocytes (eggs) improved outcomes from in vitro fertilization (IVF). It found that antioxidant media led to more good quality embryos and higher pregnancy rates than standard media. Some background IVF is an infertility procedure in which oocytes (eggs) are...
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In a nutshell This study examined if pre-treatment with immunotherapy could improve the effectiveness of following treatment for patients with hard-to-treat non-Hodgkin lymphoma (NHL). The results indicated that immunotherapies increased the effectiveness of other treatments such as chemotherapy for some patients. Some background While...
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In a nutshell This study examined if adding biological therapy rituximab (Rituxan) to chemotherapy improved treatment results for children with non-Hodgkin lymphoma. The results showed that rituximab improved patients’ chances of survival but also caused more side effects. Some background Treatment results for children with NHL have...
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In a nutshell This study investigated if the Xinyue capsule (XYC) reduces the risk of cardiovascular events (CVEs) in patients with coronary artery disease (CAD). They found that XYC combined with standard treatment reduced the risk of CVEs in these patients. Some background Coronary artery disease (CAD) is caused by blockages in...
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In a nutshell This study investigated whether combining clicks with muscle stimulation could improve hand treatment in stroke survivors. Researchers suggested that this treatment can produce a small but significant treatment improvement. Some background Stroke is a serious condition that more than doubled in low- and middle- income countries in the...
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In a nutshell This study looked at treating patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer and brain metastases (BM) with tucatinib (Tukysa) plus trastuzumab (Herceptin) and capecitabine (Xeloda). This study found that this treatment reduces the risk of cancer worsening in these...
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In a nutshell This review aimed to discuss the toxicities of ibrutinib (Imbruvica) treatment and how to manage them. This review concluded that patients should be regularly monitored for toxicities and actively treated to reduce side effects and avoid disruption to treatment. Some background Ibrutinib is a type of targeted therapy known as a...
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In a nutshell This review aimed to discuss the toxicities of ibrutinib (Imbruvica) treatment and how to manage them. This review concluded that patients should be regularly monitored for toxicities and actively treated to reduce side effects and avoid disruption to treatment. Some background Ibrutinib is a...
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In a nutshell This study aimed to compare the effectiveness and safety of generic and branded imatinib in patients with newly diagnosed chronic-phase chronic myeloid leukemia. This study concluded that generic and branded imatinib had similar effectiveness and safety in these patients. Some...
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In a nutshell This study aimed to evaluate whether single incision sling (SIS) was as effective and safe as transobturator sling (TOS) for the treatment of stress urinary incontinence in women. The main finding was that SIS was as safe and effective as the TOS. Some background Stress urinary incontinence (SUI) is the involuntary leakage of urine due...
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In a nutshell The study evaluated outcomes after stopping PEG–asparaginase (PEG-ANAse; Oncaspar) and substituting with Erwinia ASNase (Elspar) in children with B-cell acute lymphoblastic leukemia (B-ALL). The main finding was that completely stopping ASNase was associated with poorer outcomes in such patients. Some background...
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In a nutshell The study evaluated long-term outcomes of RVD involving lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (Decadron) and risk-based maintenance therapy in patients with newly diagnosed multiple myeloma (MM). The authors found this approach to be beneficial for survival in a large group of patients. Some background RVD...
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