In a nutshell This study compared two different chemotherapy treatments in metastatic colorectal cancer (mCRC; spread to other parts of the body). Researchers suggested that 24-hour infused irinotecan (Camptosar) plus oral S-1 (Teysuno) chemotherapy and bevacizumab (Avastin) is well tolerated and associated with improved outcomes. Some background...
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In a nutshell This article outlined the current guidelines for treatment for patients with classical Hodgkin lymphoma (cHL). Some background Treatments for patients with cHL have advanced in the last number of years and most patients can be cured. Treatment options include chemotherapy (CT), radiotherapy (RT), and biological...
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In a nutshell This study investigated factors affecting fertility in women with endometriosis (EDM). They found that age and infertility time were associated with pregnancy rates in these women. Some background Endometriosis (EDM) is a common condition in women. EDM is caused by uterine tissue growing outside the womb. This can cause pain...
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In a nutshell This study investigated if inhibin A (IHA) is associated with oocyte maturation (OM) during ovarian stimulation (OS). They found that IHA levels are associated with OM. Some background Infertility is an increasing problem worldwide. Assisted reproductive techniques (ART) are used to treat infertility. Controlled ovarian stimulation...
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In a nutshell This study investigated if an intensive lifestyle treatment (ILT) improves stage I hypertension. They found that ILT improved blood pressure (BP) control and arterial stiffness (AS). Some background Hypertension or high blood pressure (BP) is a common condition. Hypertension with no obvious causes is called essential...
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In a nutshell This study investigated treatment tapering strategies (TTS) in patients with rheumatoid arthritis (RA). They found that drug-free remission (DFR) can be achieved in a small number of patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by excessive inflammation. This leads to painful swelling in...
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In a nutshell The study compared the long-term effects of moderate hypofractionated intensity-modulated radiation therapy (H-IMRT) and conventionally fractionated IMRT (C-IMRT) on outcomes in patients with localized prostate cancer (PC). The authors found that H-IMRT was similarly effective compared to C-IMRT after 10 years of therapy in such...
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In a nutshell The study monitored the occurrence of possible immune-related side effects (irSEs) in patients with advanced melanoma under single and combination therapy of ipilimumab (I; Yervoy), nivolumab (N; Opdivo), and pembrolizumab (P; Keytruda). The authors found that combination therapy increases the frequency of irSEs. Some background...
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In a nutshell This study investigated a combined Stop GnRH agonist and multiple-dose GnRH antagonist protocol for patients with a previous poor ovarian response (POR). It found that this protocol may lead to a higher number of oocytes collected. Some background Patients with POR produce few oocytes (eggs) in response to ovarian stimulation (OS)...
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In a nutshell This study compared modified natural cycle to stimulated cycle prior to the transfer of a frozen embryo. It found that birth rates were similar for both methods, although there was a trend toward increased early pregnancy loss with STC. Some background In vitro fertilization (IVF) is an infertility treatment which stimulates the ovaries...
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In a nutshell This study reviewed the effectiveness and safety of vibegron in the treatment of overactive bladder (OAB). Researchers suggested that vibegron was associated with improved OAB symptoms and was well tolerated. Some background OAB consists of a frequent and sudden urge to urinate that may be difficult to control. It is present in 18.6% of...
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In a nutshell The study evaluated the contribution of chemotherapy on cancer-related cognitive impairment (CRCI) reported by women with early breast cancer. The authors found that chemotherapy added to hormonal therapy caused early and short-term CRCI in such patients, compared to hormonal therapy alone. Some background CRCI refers to problems in...
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