In a nutshell This study aimed to investigate the impact of time to response to treatment on the outcomes of patients with accelerated-phase chronic myeloid leukemia. This study concluded that an early response to treatment is strongly associated with long-term survival in these patients. Some background Tyrosine...
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Vibegron improves the treatment outcomes of patients with overactive bladder
In a nutshell This study investigated the effectiveness and safety of vibegron in the treatment of overactive bladder (OAB). Researchers suggested that this drug is a good and safe option for the treatment of OAB. Some background Around 17% of adults experience OAB in Europe and the USA. OAB consists of frequent and sudden urge to urinate that is...
Read MoreCetuximab combined with chemotherapy improves the outcomes of patients with advanced colorectal cancer
In a nutshell This study investigated the effectiveness of cetuximab (Erbitux) in combination with chemotherapy for the treatment of advanced colorectal cancer (CRC). Researchers suggested that this combined treatment improves the outcomes of patients with CRC. Some background CRC is one of the most common cancers worldwide. Around 15 to 25% of...
Read MoreNocturia increases the risk of falls and fractures
In a nutshell This study reviewed the association between nocturia and falls and fractures. Researchers suggested that nocturia is associated with a 1.2-fold increased risk of falls and a 1.3-fold increase in fractures. Some background Nocturia consists of waking up more than one time each night to urinate. It is one of the most common urinary...
Read MoreIs body weight associated with a risk of ectopic pregnancy?
In a nutshell This study looked at how bodyweight affected ectopic pregnancy (EP) in women undergoing in vitro fertilization (IVF). It found that women with a low body weight have a higher rate of EP. Some background An ectopic pregnancy (EP) occurs when an embryo implants somewhere other than in the uterus. It occurs most often in the Fallopian...
Read MoreDoes follicle stimulating hormone dose affect pregnancy outcomes with oocyte donation?
In a nutshell This study investigated if the follicle-stimulating hormone (FSH) dose is associated with pregnancy outcomes during oocyte donation (OD). They found that higher FSH doses were associated with reduced live birth rates (LBR). Some background Infertility is an increasing problem for couples. Assisted reproduction (AR)...
Read MoreDoes physical activity and sedentary behavior affect pregnancy outcomes after assisted reproduction?
In a nutshell This study investigated if physical activity (PA) or sedentary behavior (SB) affect fertility outcomes in women undergoing assisted reproduction (AR). They found that PA and SB during AR did not affect fertility outcomes, while higher PA before AR was associated with higher ovarian response to stimulation. Some background...
Read MoreFresh vs. frozen embryo transfer – what is the effect of ovarian response on live birth rates?
In a nutshell This study investigated if ovarian response (OR) has an effect on pregnancy outcomes after embryo transfer (ET). They found that frozen ET (fzET) was associated with better pregnancy outcomes in women with high OR. Some background Assisted reproduction (AR) is used to treat infertility. It involves a number of steps. Controlled...
Read MoreAdapted resistance training improves freezing of gait in patients with Parkinson’s disease
In a nutshell This study investigated whether resistance training improves freezing of gait (FOG) severity in patients with Parkinson's disease (PD). Researchers suggested that adapted resistance training significantly improves the outcomes of FOG. Some background Parkinson's disease (PD) is a chronic disorder that affects the brain. Brain...
Read MoreHearing loss in rheumatoid arthritis – a review of the evidence
In a nutshell This study investigated hearing loss (HL) in patients with rheumatoid arthritis (RA). They found that RA was associated with senorineural HL (SNHL). Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by excessive inflammation. This leads to painful swelling in the joints. This causes degeneration of...
Read MoreThe effects of cholesterol-lowering drugs on breast cancer relapse in postmenopausal women under aromatase inhibitor treatment
In a nutshell The study evaluated the link between statin (cholesterol-lowering drugs) use and risks of breast cancer (BC) relapse under adjuvant aromatase inhibitors (AI) therapy in women after their menopause. The main finding was that statin use was related with lower risks of BC relapse in such patients. Some background Women with...
Read MoreDoes insulin glargine-300 reduce the risk of hypoglycemia in patients with type 1 diabetes?
In a nutshell This study compared the risk of severe hypoglycemia (dangerously low blood glucose levels) with insulin glargine-100 (Lantus) and insulin glargine-300 (Toujeo) for patients with type 1 diabetes (T1D). It found that both medications improved glucose control, and insulin glargine-300 had a lower risk of hypoglycemia. Some background T1D is...
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